299 Results for "

cell division

" in MedChemExpress (MCE) Product Catalog:
Products (299)

299 Results for "cell division" in MCE Product Catalog:

119
119 Publications Verification
製品番号: HY-D0938
CAS 番号: 150347-59-4
別名: CFSE; 5(6)-Carboxyfluorescein diacetate succinimidyl ester; 5(6)-CFDA N-succinmidyl ester
CFDA-SE is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus . CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
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80
80 Cited Publications
製品番号: HY-14519B
CAS 番号: 133073-73-1
純度:  98.41%
別名: Amethopterin hydrate; CL14377 hydrate; WR19039 hydrate
Methotrexate hydrate is a substance that affects cell growth and division. It is commonly used to fight certain diseases, especially cancer and autoimmune diseases. It works by inhibiting the process by which cells synthesize DNA.
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29
29 Cited Publications
製品番号: HY-N7452
CAS 番号: 4434-05-3
Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. Coumermycin A1 shows anti-orthopoxvirus activity.
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17
17 Cited Publications
製品番号: HY-N6733
CAS 番号: 38966-21-1
Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line .
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14
14 Cited Publications
製品番号: HY-18062
CAS 番号: 58-14-0
別名: Pirimecidan; Pirimetamin; RP 4753
Target:  

Antifolate Parasite

研究分野:  

Infection Cancer

Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic–folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate .
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13
13 Cited Publications
製品番号: HY-100888
CAS 番号: 1330782-76-7
純度:  99.94%
別名: TAK-931
Target:  

CDK

研究分野:  

Cancer

Simurosertib (TAK-931) is an orally active, selective and ATP-competitive cell division cycle 7 (CDC7) kinase inhibitor, with an IC50 of <0.3 nM. Simurosertib has anti-cancer activity .
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7
7 Cited Publications
製品番号: HY-N0160
CAS 番号: 525-79-1
別名: 6-Furfuryladenine; N6-Furfuryladenine
Kinetin (N6-furfuryladenine) belongs to the family of N6-substituted adenine derivatives known as cytokinins, which are plant hormones involved in cell division, differentiation and other physiological processes. Kinetin has anti-aging effects .
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6
6 Cited Publications
製品番号: HY-12454
CAS 番号: 796073-69-3
純度:  99.64%
別名: Ravtansine
研究分野:  

Cancer

DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody agent conjugate.
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6
6 Cited Publications
製品番号: HY-17563
CAS 番号: 961-07-9
別名: Deoxyguanosine; Guanine deoxyriboside
Target:  

Endogenous Metabolite

研究分野:  

Cancer

2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .
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6
6 Cited Publications
製品番号: HY-126542
CAS 番号: 2378855-09-3
純度:  99.47%
Target:  

VRK

研究分野:  

Neurological Disease

VRK-IN-1 is a potent and selective inhibitor of vaccinia-related kinases 1 (VRK1), with an IC50 of 150 nM. VRK1 is human Ser/Thr protein kinases associated with increased cell division and neurological disorders .
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5
5 Cited Publications
製品番号: HY-124306
CAS 番号: 496775-95-2
純度:  99.75%
別名: CID-888706
Target:  

Ras

研究分野:  

Cancer

ML-099 (CID-888706) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, Rab7, and Rab-2A .
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4
4 Cited Publications
製品番号: HY-B0941
CAS 番号: 1214-39-7
別名: Benzyladenine; 6-BAP; N6-Benzyladenine
6-Benzylaminopurine (Benzyladenine) is a cytokinin that causes plant growth and development by stimulating cell division and inhibiting respiratory kinases, thereby prolonging the preservation of green vegetables .
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4
4 Cited Publications
製品番号: HY-111548
CAS 番号: 2351882-11-4
純度:  98.61%
Target:  

Microtubule/Tubulin

研究分野:  

Others

Spastazoline is a selective spastin (a microtubule-severing AAA protein) inhibitor, with an IC50 of 99 nM for Human spastin. Spastazoline can be used for cell division- and intracellular vesicle transport-related research .
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4
4 Cited Publications
製品番号: HY-N5034
CAS 番号: 1071-23-4
別名: Monoaminoethyl phosphate; NSC 254167; O-Phosphoethanolamine
Phosphorylethanolamine (Monoaminoethyl phosphate) is a membrane phospholipid and an important precursor of Phosphatidylcholine (HY-B2233B). It is found in most animal tissues and various human extracranial tumors, playing a critical role in membrane integrity, cell division, mitochondrial respiratory function, and more. Studies have shown that changes in the abundance of Phosphorylethanolamine are associated with Alzheimer's disease and Parkinson's disease. Lowering the ratio of Phosphorylethanolamine to Phosphatidylcholine in the liver can improve insulin signaling. Phosphorylethanolamine holds promise for research in the fields of cancer, neurodegenerative disorders, and metabolic diseases .
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3
3 Cited Publications
製品番号: HY-19700
CAS 番号: 1637-39-4
trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.
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3
3 Cited Publications
製品番号: HY-P9980
CAS 番号: 2061894-48-0
別名: GSK2857914

研究分野:  

Cancer

Belantamab (GSK2857916) is a humanized IgG1 anti-BCMA/TNFRSF17 monoclonal antibody. Belantamab is linked to MMAF (HY-15579) through a non-cleavable ADC linker to synthesize the antibody-active molecule conjugate (ADC) Belantamab mafodotin (HY-P3239). After binding to BCMA on the surface of tumor cells, Belantamab mafodotin enters the cell through receptor-mediated endocytosis. After entering the cell, Belantamab mafodotin releases MMAF, blocks cell division by inhibiting tubulin polymerization, arrests the cell cycle and induces cell apoptosis. Belantamab can be used for the study of multiple myeloma, especially relapsed/refractory multiple myeloma .
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2
2 Cited Publications
製品番号: HY-118208
CAS 番号: 743456-83-9
純度:  99.90%
別名: CID-2160985
Target:  

Ras

研究分野:  

Cancer

ML-097 (CID-2160985) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, and Rab7 .
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2
2 Cited Publications
製品番号: HY-P80611
別名: CDK1; CDC2; CDC28A; CDKN1; P34CDC2; Cyclin-dependent kinase 1; CDK1; cell division control protein 2 homolog; cell division protein kinase 1; p34 protein kinase

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human

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2
2 Cited Publications
製品番号: HY-108420
CAS 番号: 6314-70-1
純度:  98.10%
Target:  

CDK

研究分野:  

Cancer

INK4C-IN-2 is a p18 INK4C inhibitor. NK4C-IN-2 promotes hematopoietic stem cells (HSCs) division by inhibiting INK4C and activating CDK4/6, with an ED50 of 5.21 nM. INK4C-IN-2 shows no cytotoxic to normal 32D cells, HSCs, leukemia cell lines and myeloma cell lines .
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1
1 Cited Publications
製品番号: HY-121497
CAS 番号: 5813-86-5
純度:  99.40%
別名: 3-MBA
Target:  

PARP Bacterial

研究分野:  

Cancer

3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells . 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum) .
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