Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
143 Results for "
free radical oxidation
" in MedChemExpress (MCE) Product Catalog:
Products (143)
143 Results for "free radical oxidation" in MCE Product Catalog:
23
23
7
Research Areas:
Famotidine (MK-208) is an orally active and highly selective histamine H2 receptor antagonist. It inhibits gastric acid secretion by blocking the Gs signaling pathway, and regulates intracellular cAMP and ERK pathways. Famotidine inhibits TLR3-mediated inflammatory pathways, and reduces the expression of various inflammatory mediators and interferon-related genes. Famotidine scavenges DPPH and nitric oxide free radicals, alleviates oxidative stress damage in gastric tissue, inhibits proMMP-9, improves vascular endothelial permeability, and restores the normal physiological functions of neutrophils and eosinophils. Famotidine crosses intestinal epithelial cells via facilitated diffusion and passive diffusion, blocks paracellular cation transport, and increases intestinal transepithelial electrical resistance. Famotidine reduces serum levels of transaminases and alkaline phosphatase, exerts analgesic effects and gastric protective effects simultaneously. Famotidine can be used in studies related to COVID-19, liver injury and acute gastric ulcer .
4
Category:
Human Gut Microbiota Metabolites Polysaccharides Metabolic Disease Plants Compositae Extract Endogenous metabolite Disease Research Fields Sophora tomentosa L. Saccharides
Target:
3
Target:
Environmental Pollutants Herbicide Autophagy Reactive Oxygen Species (ROS) Mitochondrial Metabolism
Research Areas:
Diquat dibromide is a comprehensive herbicide. Diquat dibromide increases the production of ROS and triggers mitochondrial Autophagy. Diquat dibromide generates free radicals such as superoxide anions through redox cycles, which induce oxidative stress. Diquat dibromide is cytotoxic, reproductive, and neurotoxic. Diquat dibromide is used in cotton, soybean, and other crops to combat noxious weeds .
3
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
Diquat dibromide hydrate is a comprehensive herbicide. Diquat dibromide hydrate increases the production of ROS and triggers mitophagy. Diquat dibromide hydrate generates free radicals such as superoxide anions through redox cycles, which induce oxidative stress. Diquat dibromide hydrate is cytotoxic, reproductive, and neurotoxic. Diquat dibromide hydrate is used in cotton, soybean, and other crops to combat noxious weeds .
2
2 Cited Publications
Synonyms: 1-O-hexyl-2,3,5-trimethylhydroquinone; HX-1171; BTT-105
Target:
Research Areas:
HTHQ (1-O-hexyl-2,3,5-trimethylhydroquinone) is a potent lipophilic phenolic antioxidant. HTHQ has considerable anti-oxidative activity by directly reacting with reactive oxygen species (ROS) and scavenging ROS to form more stable free radicals .
2
1
1 Cited Publications
Cat. No.: HY-W004520
CAS No.: 299-11-6
Synonyms: 5-Methylphenazinium methylsulfate
Target:
Research Areas:
Phenazine methylsulfate is a free radical generator that can act as an electron transfer reactant in cell viability assays. It also has insecticidal properties. Furthermore, Phenazine methylsulfate induces oxidative DNA damage and cell apoptosis, showing antitumor activity .
1
1 Cited Publications
1
1 Cited Publications
Synonyms: Dimethylglycine; DMG; N-Methylsarcosine
1
1 Cited Publications
Target:
Research Areas:
Calcium dobesilate is a vascular protector with oral activity that can clear hydroxyl free radicals, with an IC50 of 1.1 pM. Calcium dobesilate has antioxidant activity and helps to reduce oxidative stress and inflammation in the retinas of diabetic mice. Calcium dobesilate can be used to study chronic venous diseases, diabetic retinopathy, and the occurrence of hemorrhoids, among other conditions .
1
1 Cited Publications
Cat. No.: HY-B2130S1
CAS No.: 62948-75-8
Uric acid- 15N2 is the 15N-labeled Uric acid (HY-B2130). Uric acid is an orally active oxygen free radical scavenger that helps maintain stable blood pressure and combat oxidative stress. Uric acid can scavenge ROS, such as singlet oxygen and peroxynitrite, and inhibit lipid peroxidation. Uric acid can be used as a modeling agent in research on hyperuricemia-induced hypertension models .
1
1
1 Cited Publications
Cat. No.: HY-W001158
CAS No.: 2491-06-7
Synonyms: Dimethylglycine hydrochloride; DMG hydrochloride; N-Methylsarcosine hydrochloride
Research Areas:
1
1 Cited Publications
Synonyms: Dimethylglycine (Standard); DMG (Standard); N-Methylsarcosine (Standard)
1
1
Category:
Convolvulaceae Extract Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Plants Ipomoea batatas (Linn.) Lamarck
Target:
Cat. No.: HY-W013507
CAS No.: 39924-52-2
Cat. No.: HY-W011956
CAS No.: 2208-41-5
Target:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
