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mRNA

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153084A
    CD19 CAR mRNA (Human)
    1 Publications Verification

    mRNA CD19 Cancer
    CD19 CAR mRNA (Human) expresses CAR protein that specifically targets human CD19. CD19 CAR mRNA can trigger transitory expression of CAR, allowing T cells to be targeted without permanent genetic modification. CD19 CAR mRNA targets CD19 which is a transmembrane glycoprotein primarily expressed on B lymphocytes and is important in B cell activation. CD19 CAR mRNA can be studied in cancer research such as lymphoma and leukemia .
    CD19 CAR mRNA (Human)
  • HY-153229
    Firefly luciferase mRNA-LNP
    1 Publications Verification

    mRNA Biochemical Assay Reagents Others
    Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing firefly luciferase mRNA. Firefly luciferase mRNA-LNP exhibits a stable nanostructure, in which LNP plays a key role in effectively protecting and transporting mRNA to cells. Luciferase is a bioluminescent reporter gene for gene regulation and functional studies. Firefly Luciferase mRNA-LNP expresses firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Firefly luciferase mRNA-LNP is studied in research for RNA delivery, cell viability, and translation efficiency .
    Firefly luciferase mRNA-LNP
  • HY-153080

    Fluorescent Dye mRNA Others
    Firefly Luciferase mRNA (N1-Me-Pseudo UTP) is a modified form of firefly luciferase mRNA, which is N1-methylated pseudo uridine (N1-Me-Pseudo UTP). Firefly Luciferase mRNA (N1-Me-Pseudo UTP) is a commonly used reporter molecule in biomedical and mRNA research and its core function is to rapidly and quantitatively monitor the expression and delivery efficiency of mRNA through the emission of light signals .
    Firefly Luciferase mRNA(N1-Me-Pseudo UTP)
  • HY-153235

    mRNA SARS-CoV Liposome Infection
    COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing mRNA encoding COVID-19 Spike Protein. COVID-19 Spike Protein undertakes the functions of virus binding with host cell receptors, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design. COVID-19 Spike Protein mRNA-LNP can be used for RNA delivery, vaccine formulation and design targeting SARS-CoV-2 .
    COVID-19 Spike Protein mRNA-LNP
  • HY-171493

    Biochemical Assay Reagents Others
    mCherry mRNA(N1-Me-Pseudo UTP) is a reporter mRNA encoding a red fluorescent protein, suitable for gene expression analysis, cell viability assays, and in vivo imaging. mCherry, derived from mushroom coral, is a widely used red fluorescent protein tracer in biotechnology applications.
    mCherry mRNA(N1-Me-Pseudo UTP)
  • HY-174790

    mRNA Cancer
    Firefly Luciferase mRNA is a reporter mRNA that can be transfected into cells to express firefly luciferase protein. Firefly Luciferase mRNA induces cytotoxicity in cancer cells at low concentrations. In cancer cells, the expression level of luciferase shows a non-linear relationship with the dose of Firefly Luciferase mRNA. When combined with the H2S-responsive bioluminescent probe (H-Luc), Firefly Luciferase mRNA enables bioluminescence-based detection of endogenous hydrogen sulfide in non-transgenic NAFLD cell models and NAFLD mouse models. Firefly Luciferase mRNA can be used in studies related to non-alcoholic fatty liver disease .
    Firefly Luciferase mRNA
  • HY-174646

    mRNA Inflammation/Immunology
    Human IL10 mRNA is the messenger ribonucleic acid that encodes human IL-10. The expression of IL-10 mRNA is highly inducible and cell type-specific.
    Human IL10 mRNA
  • HY-153231A

    Fluorescent Dye Liposome Others
    eGFP mRNA-LNP (500 ng/μL) is a lipid nanoparticle (LNP) containing eGFP mRNA. eGFP mRNA-LNP carries Enhanced Green Fluorescent Protein (eGFP), which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry (excitation wavelength = 488 nm; emission wavelength = 535/40 bandpass). eGFP mRNA-LNP can be used for RNA delivery, translation efficiency and cell viability .
    eGFP mRNA-LNP (500 ng/μL)
  • HY-150742A

    Toll-like Receptor (TLR) Inflammation/Immunology
    ODN 2336 sodium is a A-Class CpG ODN (oligodeoxynucleotides), is a potent TLR9 agonist. ODN 2336 sodium induces the production of IFN-α. ODN 2336 sodium up-regulates the expression of IP-10 mRNA and IL-18 mRNA. ODN 2336 sodium can be used as adjuvant of vaccines .
    ODN 2336 sodium
  • HY-174655

    mRNA Metabolic Disease
    Human IGF1 mRNA encodes the human insulin like growth factor 1 (IGF1) protein which is involved in mediating growth and development.
    Human IGF1 mRNA
  • HY-E70081

    Biochemical Assay Reagents Others
    mRNA Cap 2'-O-methyltransferase uses S-adenosylmethionine (SAM) as a methyl donor to add a methyl group at the 2'-O position of the first nucleotide at the 5’ end of Cap-0 mRNA, resulting in Cap-1 structure. Cap-1 structure promotes translation efficiency, increasing subsequent protein expression .
    mRNA Cap 2'-O-methyltransferase
  • HY-174795

    mRNA Others
    mCherry mRNA encodes the mCherry fluorescent protein, which is derived from Anaplasma marginale. mCherry can be used as a fluorescent tracer in transfection and transgenic experiments or as a reporter of gene expression.
    mCherry mRNA
  • HY-174485

    mRNA Others
    OVA mRNA encodes the ovalbumin (OVA) protein, a member of the serpin superfamily and the predominant glycoprotein found in egg whites. It is a commonly used antigen for immunization and biochemical studies and is an established model allergen for airway hyper-responsiveness.
    OVA mRNA
  • HY-174789

    mRNA Others
    Gaussia luciferase (GLuc) mRNA will express a luciferase protein, derived from the Gaussia princeps. luciferases are widely used in biotechnology, for microscopy and as reporter genes, for many of the same applications as fluorescent proteins.
    Gaussia luciferase mRNA
  • HY-150742

    Toll-like Receptor (TLR) Inflammation/Immunology
    ODN 2336 is a A-Class CpG ODN (oligodeoxynucleotides), is a potent TLR9 agonist. ODN 2336 induces the production of IFN-α. ODN 2336 up-regulates the expression of IP-10 mRNA and IL-18 mRNA. ODN 2336 can be used as adjuvant of vaccines .
    ODN 2336
  • HY-174495

    mRNA Others
    Human EPO mRNA encodes the human erythropoietin (EPO) protein, a hormone that controls erythropoiesis, or red blood cell production. EPO also plays a role in wound healing and the brain’s response to neural injury. Kariko et al. showed that transfection of EPO mRNA in vivo resulted in significant increases of both reticulocyte counts and hematocrits.
    Human EPO mRNA
  • HY-150358

    Beta-galactosidase mRNA

    mRNA Others
    β-galactosidase mRNA encodes β-galactosidase, a protein product of the bacterial LacZ gene. β-galactosidase catalyzes the conversion of β-galactosides into monosaccharides which could be used as a common marker to assess transfection efficiency.
    β-galactosidase mRNA
  • HY-174510

    mRNA Cancer
    Human VEGFA mRNA encodes the human vascular endothelial growth factor A (VEGFA) protein, a member of the PDGF/VEGF growth factor family. VEGFA could induce proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis.
    Human VEGFA mRNA
  • HY-177608

    Interleukin Related Inflammation/Immunology
    Rat IL-10 mRNA encodes interleukin-10 (IL-10). IL-10 is expressed in tissues/cells such as hepatic stellate cells and is involved in physiological processes including liver fibrosis.
    Rat IL10 mRNA
  • HY-174486

    mRNA Others
    mCherry mRNA (5moU) encodes the fluorescent protein, mCherry, which is derived from DsRed, a protein found in Discosoma sp. mCherry is a monomeric fluorophore with a peak absorption at 587 nm and emission at 610 nm. It is stable and resistant to photobleaching.
    mCherry mRNA (5moU)
  • HY-150361

    mRNA Cancer
    Mouse Tert mRNA encodes the mouse telomerase reverse transcriptase (Tert) protein that plays important roles in aging and antiapoptosis.
    Mouse Tert mRNA
  • HY-174722

    mRNA Cancer
    Human DCT mRNA encodes the human dopachrome tautomerase (DCT) protein, which is involved in regulating eumelanin and phaeomelanin levels.
    Human DCT mRNA
  • HY-174501

    Beta-galactosidase mRNA (5moU)

    mRNA Others
    β-galactosidase mRNA (5moU) encodes β-galactosidase, a protein product of the bacterial LacZ gene. β-galactosidase catalyzes the conversion of β-galactosides into monosaccharides which could be used as a common marker to assess transfection efficiency. The incorporation of 5moU can reduce the immunogenicity of the resulting mRNA.
    β-galactosidase mRNA (5moU)
  • HY-174578

    mRNA Cancer
    Human MYB mRNA encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. MYB plays an essential role in the regulation of hematopoiesis.
    Human MYB mRNA
  • HY-174500

    mRNA Others
    The eSpCas9 mRNA expresses enhanced-specificity SpCas9 protein, with sequence originally from Slaymaker et al Science. 2015 Dec 1.
    eSpCas9 mRNA
  • HY-174576

    mRNA Inflammation/Immunology
    Human MYDGF mRNA encodes the human myeloid derived growth factor (MYDGF) protein. MYDGF was previously thought to support proliferation of lymphoid cells and was considered an interleukin.
    Human MYDGF mRNA
  • HY-174667

    mRNA Cancer
    Human IFNA4 mRNA encodes the human interferon alpha 4 (IFNA4) protein, which may have antiviral activities.
    Human IFNA4 mRNA
  • HY-174773

    mRNA Metabolic Disease
    Human BTC mRNA encodes the human betacellulin (BTC) protein, a member of the epidermal growth factor family. BTC promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability.
    Human BTC mRNA
  • HY-174719

    mRNA Inflammation/Immunology
    Human ELANE mRNA encodes the human elastase (ELANE) protein, a member of serine proteases family. ELANE may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin.
    Human ELANE mRNA
  • HY-174624

    mRNA Inflammation/Immunology
    Human IL20 mRNA encodes the human interleukin 20 (IL20) protein, a proinflammatory and angiogenic cytokine that may involves in epidermal function and psoriasis.
    Human IL20 mRNA
  • HY-174682

    mRNA Cancer
    Human FOS mRNA encodes the human Fos proto-oncogene, AP-1 transcription factor subunit (FOS) protein which has been implicated as regulators of cell proliferation, differentiation, and transformation.
    Human FOS mRNA
  • HY-174535

    mRNA Cancer
    Human TGFA mRNA encodes the human transforming growth factor alpha (TGFA) protein. TGFA is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development.
    Human TGFA mRNA
  • HY-174780

    mRNA Cancer
    Human AMHR2 mRNA encodes the human anti-Mullerian hormone receptor type 2 (AMHR2) protein, a receptor for the anti-Mullerian hormone (AMH).
    Human AMHR2 mRNA
  • HY-174537

    mRNA Cancer
    Human TERT mRNA encodes the human telomerase reverse transcriptase (TERT) protein, a catalytic subunit of the enzyme telomerase, which, together with the telomerase RNA component (TERC), comprises the most important unit of the telomerase complex.
    Human TERT mRNA
  • HY-174661

    mRNA Inflammation/Immunology
    Human IFNK mRNA encodes the human interferon kappa (IFNK) protein, a member of the type I interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections.
    Human IFNK mRNA
  • HY-174716

    mRNA Inflammation/Immunology
    Human EREG mRNA encodes the human epiregulin (EREG) protein, a member of the epidermal growth factor family. EREG may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation.
    Human EREG mRNA
  • HY-174634

    mRNA Inflammation/Immunology
    Human IL16 mRNA encodes the human interleukin 16 (IL16) protein, a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication.
    Human IL16 mRNA
  • HY-174608

    mRNA Inflammation/Immunology
    Human IL32 mRNA encodes the human interleukin 32 (IL32) protein, a member of the cytokine family. IL32 induces the production of TNFalpha from macrophage cells.
    Human IL32 mRNA
  • HY-174509

    mRNA Cancer
    Human VEGFB mRNA encodes the human vascular endothelial growth factor B (VEGFB) protein, a member of the platelet-derived growth factor (PDGF)/ vascular endothelial growth factor (VEGF) family. VEGFB is a growth factor for endothelial cells.
    Human VEGFB mRNA
  • HY-177447

    mRNA NOD-like Receptor (NLR) Inflammation/Immunology
    Human NLRP3 mRNA encodes the human NLRP3 protein, an inflammasome. NLRP3 belongs to the NLR protein family and plays a crucial role in immunity and human disease .
    Human NLRP3 mRNA
  • HY-174593

    mRNA Cancer
    Human KDR mRNA encodes the human kinase insert domain receptor (KDR) protein, a receptor of vascular endothelial growth factor (VEGF). KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting.
    Human KDR mRNA
  • HY-174553

    mRNA Cancer
    Human PDGFA mRNA encodes the human platelet derived growth factor A (PDGFA) protein, a member of the platelet-derived growth factor family. PDGFA plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.
    Human PDGFA mRNA
  • HY-174596

    mRNA Inflammation/Immunology
    Human IL9 mRNA encodes the human interleukin 9 (IL9) protein, a cytokine that acts as a regulator of a variety of hematopoietic cells. IL9 stimulates cell proliferation and prevents apoptosis.
    Human IL9 mRNA
  • HY-174769

    mRNA Inflammation/Immunology
    Human CCL14 mRNA encodes the human C-C motif chemokine ligand 14 (CCL14) protein, a cytokine that induces changes in intracellular calcium concentration and enzyme release in monocytes.
    Human CCL14 mRNA
  • HY-174552

    mRNA Cancer
    Human PDGFB mRNA encodes the human platelet derived growth factor B (PDGFB) protein, a member of the platelet-derived growth factor family. PDGFB plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.
    Human PDGFB mRNA
  • HY-174550

    mRNA Cancer
    Human PDGFD mRNA encodes the human platelet derived growth factor D (PDGFD) protein, a member of the platelet-derived growth factor family. PDGFD plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.
    Human PDGFD mRNA
  • HY-174551

    mRNA Cancer
    Human PDGFC mRNA encodes the human platelet derived growth factor C (PDGFC) protein, a member of the platelet-derived growth factor family. PDGFC plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.
    Human PDGFC mRNA
  • HY-150144

    DNA/RNA Synthesis Others
    Uracil-m7GpppAmpG ammonium solution (100 mM) is a cap analog that can be used for mRNA synthesis.
    Uracil-m7GpppAmpG ammonium solution (100 mM)
  • HY-174666

    mRNA Cancer
    Human IFNAR1 mRNA encodes the human interferon alpha and beta receptor subunit 1 (IFNAR1) protein, a protein that belongs to the type II cytokine receptor family and functions as an antiviral factor.
    Human IFNAR1 mRNA
  • HY-174734

    mRNA Inflammation/Immunology
    Human CSF1 mRNA encodes the human colony stimulating factor 1 (CSF1) protein, a cytokine that controls the production, differentiation, and function of macrophages. CSF1 may be involved in the development of the placenta.
    Human CSF1 mRNA

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