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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
oxidative modification
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "oxidative modification" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-N10574
CAS No.: 72496-59-4
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1
1 Cited Publications
Cat. No.: HY-N10574A
CAS No.: 86496-18-6
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Synonyms: Ciprofol; HSK3486
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Cipepofol (Ciprofol), a novel 2,6-disubstituted phenol derivative, is a positive allosteric modulator and direct agonist of the GABAA receptor. Cipepofol can cause the central nerve inhibition and promote sleep based on the structural modification of Propofol (HY-B0649). Cipepofol can activate the sirtuin1 (Sirt1)/Nrf2 pathway. Cipepofol protects the heart against Isoproterenol (ISO; HY-B0468)-induced myocardial infarction by reducing cardiac oxidative stress, inflammatory response and cardiomyocyte apoptosis .
Cat. No.: HY-W011696
CAS No.: 112-90-3
Synonyms: cis-1-Amino-9-octadecene, 80-90%
Cat. No.: HY-W116606
CAS No.: 1357078-03-5
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Coumarin boronic acid is a fluorescent probe. The excitation and emission wavelengths of coumarin boronic acid are set to 360 nm and 430 nm, respectively. Coumarin boronic acid can be used to monitor the formation of amino acid and protein hydroxyl peroxides in real time, which is beneficial for understanding the mechanisms of oxidative stress and protein post-translational modification .
Cat. No.: HY-W011168
CAS No.: 13389-03-2
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8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H2O2-Cl --Br - system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation .
Cat. No.: HY-NP143
CAS No.: 93928-24-6
Cat. No.: HY-W087905
CAS No.: 1889-67-4
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2,3-Dimethyl-2,3-diphenylbutane is a minor product formed during the thermal decomposition of dicumyl peroxide (DCP) in cumene, generated through radical coupling reactions. As an initiator capable of producing free radicals, 2,3-dimethyl-2,3-diphenylbutane promotes cross-linking or decomposition processes via initiating free radical reactions in fields such as polymer polymerization (e.g., modification of polyphenylene oxide processing), organic synthesis (e.g., DCP decomposition reactions), and coal processing (e.g., oxidation stabilization of coal tar pitch), thereby enhancing material properties or reaction efficiency .
Cat. No.: HY-112817
CAS No.: 139307-94-1
Synonyms: 8-Oxo-Deoxyguanosine triphosphate
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Cat. No.: HY-N4031
CAS No.: 82375-29-9
Cat. No.: HY-D2575
CAS No.: 3052492-38-0
Cat. No.: HY-D2871
CAS No.: 1866495-46-6
Cat. No.: HY-100096A
CAS No.: 2733287-29-9
Synonyms: (Rac)-Emtricitabine sulfoxide; (Rac)-Emtricitabine Degradant-III
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(Rac)-Emtricitabine S-oxide ((Rac)-Emtricitabine sulfoxide; (Rac)-Emtricitabine Degradant-III) is Emtricitabine S-oxide (HY-100096) racemic modification. Emtricitabine S-oxide is a major degradation product of Emtricitabine. Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.
Cat. No.: HY-123260
CAS No.: 144754-35-8
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S12340 is a a inhibitor of the oxidative modification of low-density lipoprotein and shows protective effect on cardiac cells exposed to oxidative stress .
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Phenylphosphinic acid binds to metal oxide surfaces for a modification and functionalization. Phenylphosphinic acid can also be used for nanoparticles or sol-gel synthesis .
Cat. No.: HY-124209
CAS No.: 156406-33-6
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9-keto Fluprostenol is an analog of prostaglandin E2 (PGE2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. It is anticipated that this analog will have strong affinity for EP receptors and act as a PGE2 agonist.
Cat. No.: HY-126911
CAS No.: 62145-07-7
Synonyms: Fluprostenol Prostaglandin D2
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11-keto Fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-11 of fluprostenol yields 11-keto fluprostenol. 11-keto Fluprostenol exhibits moderate binding to the CRTH2/DP2 receptor compared to PGD2 and essentially no activity at the DP1 receptor.
Cat. No.: HY-W767399
Cat. No.: HY-184622
PEGylated iron oxide nanoparticles (carboxyl-terminated) (10-50 nm) are prepared by high-temperature pyrolysis and then modified with PEG-carboxyl-terminated iron oxide. This modification transforms the nanoparticles from an oil phase to an aqueous phase, thus broadening their applications in the biological field. The iron oxide used in the 100 nm nanoparticles is prepared by a solvothermal method.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
