CDK2 modulator 1
CDK2 modulator 1 is a CDK2 modulator with an EC50 < 100 nM and an Emax > 100% of positive control in a TR-FRET proximity assay. CDK2 modulator 1 induces ternary complex formation with CDK2/CCNE1 and CRBN. CDK2 modulator 1 can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 3066623-95-5
- Formula: C30H27FN6O5
- Molecular Weight:570.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CDK2/cyclinE |
CDK2 modulator 1 (compound 248) (10-point dilution series; 2 h (room temperature)) induces ternary complex formation between purified CDK2/CCNE1 and CRBN/DDB1 proteins with an EC50 < 100 nMl[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3066623-95-5
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Molecular Weight 570.57
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Formula C30H27FN6O5
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SMILES
N#CC1=CC(C2=CC(OC)=C(C(C)(C)NC(NC3=CC=C4C(N(C5C(NC(CC5)=O)=O)CC4=C3F)=O)=O)C=C2)=CN=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK2 modulator 1 Related Classifications
HY-186126 Related Classifications
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