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Cat. No.: HY-17678

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Z-VAD-CHO

Z-VAD-CHO is a potent inhibitor of human caspase-1 with a K_i value of 0.008 μM.

For research use only. We do not sell to patients.

CAS No.: 875152-90-2
Formula: C₂₀H₂₇N₃O₇
Molecular Weight:421.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Z-VAD-CHO Chemical Structure

CAS No.: 875152-90-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Z-VAD-CHO is a potent inhibitor of human caspase-1 with a K_i value of 0.008 μM^[1].

All Caspase Isoforms :

Chemical Information

CAS No. 875152-90-2
Molecular Weight 421.44
Formula C₂₀H₂₇N₃O₇
SMILES

OC(C[C@@H](C=O)NC([C@H](C)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fahr BT,et al. Tethering identifies fragment that yields potent inhibitors of human caspase-1. Bioorg Med Chem Lett. 2006 Feb;16(3):559-62. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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Z-VAD-CHO

All Caspase Isoforms