2-Cyanoethylalsterpaullone
2-Cyanoethylalsterpaullone (compound 7) is an Alsterpaullone (HY-108359) derivative, which exhibits potent and selective inhibitory activities against CDK1/Cyclin B and GSK-3β (GSK-3β: IC50=0.8 nM; CDK1/Cyclin B: IC50=0.23 nM).
For research use only. We do not sell to patients.
- CAS No.: 852527-97-0
- Formula: C19H14N4O3
- Molecular Weight:346.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cdk1/cyclin B 0.23 nM (IC50) |
GSK-3β 0.8 nM (IC50) |
Chemical Information
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CAS No. 852527-97-0
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Molecular Weight 346.34
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Formula C19H14N4O3
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SMILES
N#CCCC1=CC=C(NC(CC2=C3NC4=C2C=C([N+]([O-])=O)C=C4)=O)C3=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)