2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. 4-Phenylcinnamic acid

4-Phenylcinnamic acid is a weak HDAC2 inhiibitor (IC50 > 5 μM). 4-Phenylcinnamic acid has weak cell growth inhibition against tumor cells.

For research use only. We do not sell to patients.

4-Phenylcinnamic acid

4-Phenylcinnamic acid Chemical Structure

CAS No. : 13026-23-8

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4-Phenylcinnamic acid Related Antibodies

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Description

4-Phenylcinnamic acid is a weak HDAC2 inhiibitor (IC50 > 5 μM). 4-Phenylcinnamic acid has weak cell growth inhibition against tumor cells[1].

IC50 & Target[1]

HDAC2

>5 μM ()

In Vitro

4-Phenylcinnamic acid (Compound 2) shows an IC50 >5 μM for HDAC2[1].
4-Phenylcinnamic acid (72 h) exhibits weak antiproliferative activity against NB4, HCT116, and H460 human tumor cell lines (IC50 >10 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

4-Phenylcinnamic acid Related Antibodies

Cell Proliferation Assay[1]

Cell Line: NB4, HCT116, H460, IGROV-1, IGROV-1/Pt1
Concentration: 0-20 μM
Incubation Time: 72 h
Result: Showed weak antiproliferative activity against HCT116, H460, and NB4 cells with IC50 >20, >20 and >10 μM.
Showed no antiproliferative activity for IGROV-1 and IGROV-1/Pt1 cells.
Molecular Weight

224.26

Formula

C15H12O2
CAS No.
Appearance

Solid

SMILES

O=C(O)C=CC=1C=CC(=CC1)C=2C=CC=CC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Purity & Documentation
References
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4-Phenylcinnamic acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Phenylcinnamic acid13026-23-8HDACHistone deacetylasesH460NB4HCT116HeLa celltumor cellsHDAC2Inhibitorinhibitorinhibit

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HY-W103792
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