1. GPCR/G Protein
    Immunology/Inflammation
  2. CCR
  3. CCR1 antagonist 8

CCR1 antagonist 8 

Cat. No.: HY-120588
Handling Instructions

CCR1 antagonist 8 (compound 19n), a third azaindazole series compound, is a CCR1 antagonist clinical candidate, with an IC50 of 1.8 nM in Ca2+ flux assay.

For research use only. We do not sell to patients.

CCR1 antagonist 8 Chemical Structure

CCR1 antagonist 8 Chemical Structure

CAS No. : 1295298-26-8

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Description

CCR1 antagonist 8 (compound 19n), a third azaindazole series compound, is a CCR1 antagonist clinical candidate, with an IC50 of 1.8 nM in Ca2+ flux assay[1].

IC50 & Target[1]

CCR1

1.8 nM (IC50, in Ca2+ flux assay)

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

451.47

Formula

C₂₂H₁₈FN₅O₃S

CAS No.

1295298-26-8

SMILES

O=C(C1=CN=CC2=C1C=NN2C3=CC=C(F)C=C3)NC4(C5=CC(S(=O)(C)=O)=NC=C5)CC4

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Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
CCR1 antagonist 8
Cat. No.:
HY-120588
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CCR1 antagonist 8

Cat. No.: HY-120588