1. Anti-infection
  2. Bacterial
  3. Ginkgolic Acid (C13:0)

Ginkgolic Acid (C13:0) (Synonyms: Ginkgolic acid (13:0); Ginkgoneolic Acid; 6-Tridecylsalicylic acid)

Cat. No.: HY-N0078 Purity: 98.95%
Handling Instructions

Ginkgolic Acid (C13:0) is a natural anticariogenic agent in that it exhibits antimicrobial activity against S.

For research use only. We do not sell to patients.

Ginkgolic Acid (C13:0) Chemical Structure

Ginkgolic Acid (C13:0) Chemical Structure

CAS No. : 20261-38-5

Size Price Stock Quantity
5 mg USD 75 In-stock
Estimated Time of Arrival: December 31
10 mg USD 125 In-stock
Estimated Time of Arrival: December 31
50 mg USD 315 In-stock
Estimated Time of Arrival: December 31
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Other Forms of Ginkgolic Acid (C13:0):

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Description

Ginkgolic Acid (C13:0) is a natural anticariogenic agent in that it exhibits antimicrobial activity against S. mutans and suppresses the specific virulence factors associated with its cariogenicity. IC50 value: Inhibiting the biofilm formation of S. mutans (MBIC (50) = 4 μg/mL); reduced 1-day-developed biofilm of S. mutans by 50 % or more at low concentration (MBRC (50) = 32 μg/mL). Target: In vitro: Ginkgolic Acid (C13:0) inhibited not only the growth of S. mutans planktonic cells at minimum inhibitory concentration (MIC) of 4 μg/mL and minimum bactericidal concentration (MBC) of 8 μg/mL but also the acid production and adherence to saliva-coated hydroxyapatite of S. mutans at sub-MIC concentration. In addition, this agent was effective in inhibiting the biofilm formation of S. mutans (MBIC (50) = 4 μg/mL), and it reduced 1-day-developed biofilm of S. mutans by 50 % or more at low concentration (MBRC (50) = 32 μg/mL). Furthermore Ginkgolic Acid (C13:0) disrupted biofilm integrity effectively [1]. In vivo:

Molecular Weight

320.47

Formula

C₂₀H₃₂O₃

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (312.04 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1204 mL 15.6021 mL 31.2042 mL
5 mM 0.6241 mL 3.1204 mL 6.2408 mL
10 mM 0.3120 mL 1.5602 mL 3.1204 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.80 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 98.95%

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Product Name:
Ginkgolic Acid (C13:0)
Cat. No.:
HY-N0078
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