1. Anti-infection
  2. Bacterial

N-Acetyl-Calicheamicin (Synonyms: N-Acetyl-Calicheamicin γ; N-Acetyl-γ-calicheamicin)

Cat. No.: HY-19791 Purity: >98.0%
Handling Instructions

N-Acetyl-Calicheamicin is a potent enediyne antitumor antibiotic.

For research use only. We do not sell to patients.
N-Acetyl-Calicheamicin Chemical Structure

N-Acetyl-Calicheamicin Chemical Structure

CAS No. : 108212-76-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 22341 In-stock
1 mg USD 2160 In-stock
5 mg USD 7200 In-stock
10 mg   Get quote  
50 mg   Get quote  

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Other Forms of N-Acetyl-Calicheamicin:

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

N-Acetyl-Calicheamicin is a potent enediyne antitumor antibiotic. Target: Antibacterial N-Acetyl-Calicheamicin is a a derivative of Calicheamicin. Calicheamicin is a naturally occurring hydrophobic enediyne antibiotic that was isolated from the actinomycete Micromonospora echinospora calichensis. Calicheamicin can interfere with biological processes not simply by cleaving free DNA but also by displacing a DNA-binding protein through competition or modulation of DNA structure.

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 0.7090 mL 3.5451 mL 7.0902 mL
5 mM 0.1418 mL 0.7090 mL 1.4180 mL
10 mM 0.0709 mL 0.3545 mL 0.7090 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

1410.39

Formula

C₅₇H₇₆IN₃O₂₂S₄

CAS No.

108212-76-6

SMILES

O[[email protected]](CC1=O)(C#C/C=C\C#C2)/C(C([[email protected]]2O[[email protected]@](O[[email protected]](C)[[email protected]@H](NO[[email protected]](O[[email protected]](C)[[email protected]]3SC(C(C(C)=C(I)C(O[[email protected]](O[[email protected]@H](C)[[email protected]](O)[[email protected]]4OC)[[email protected]@H]4O)=C5OC)=C5OC)=O)C[[email protected]@H]3O)[[email protected]@H]6O)([H])[[email protected]@H]6O[[email protected]@](OC[[email protected]@H]7N(CC)C(C)=O)([H])C[[email protected]@H]7OC)=C1NC(OC)=O)=C/CSSSC

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
N-Acetyl-Calicheamicin
Cat. No.:
HY-19791
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