2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3819):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-109714
    3,4-Benzocoumarin
    		99.57%
    3,4-Benzocoumarin is a kind of the expanded structure of coumarin derivatives.Coumarin is a chemical compound in the benzopyrone chemical class that can be found in many natural species. Coumarins possess variety of biological activities and unique photophysical properties. 3,4-Benzocoumarin, a AOH‐like compound , has the sensibility of the antibody with an IC50 of 919.2 ng/mL.
    3,4-Benzocoumarin
  • HY-P11195
    Angiopep-2 azide
    		99.47%
    Angiopep-2 azide is a peptide derivative of Angiopep-2 (HY-P2341) bearing a side chain azide (N3) group. Angiopep-2 exhibits high blood-brain barrier (BBB) penetration capability and can be used for brain compound delivery.
    Angiopep-2 azide
  • HY-W000773
    7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine
    7-Bromopyrrolotriazin-4-amine (Compound 3-7) is a pyrrolotriazine derivative. 7-Bromopyrrolotriazin-4-amine is applicable to the study of hyperproliferative diseases and angiogenesis-related diseases.
    7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine
  • HY-E70236
    CoA-S-S-CoA
    CoA-S-S-CoA is an oxidized disulfide form of Coenzyme A (HY-128851). CoA-S-S-CoA acts as a pool of disulfide reducing equivalents.
    CoA-S-S-CoA
  • HY-W003903A
    Methyl benzyl-L-serinate
    		98.19%
    Methyl benzyl-L-serinate is a serine derivative.
    Methyl benzyl-L-serinate
  • HY-W744618
    Ambrettolide
    		99.53%
    Ambrettolide is a natural macrolide compound that possesses a warm and delicate musk aroma, with a hint of animal fragrance.
    Ambrettolide
  • HY-W011180
    Vitamin A Propionate
    		98.91%
    Vitamin A Propionate is an ester compound of vitamin A. In nutritional studies of foals, different doses have different effects on growth, serum biochemistry and hematological indicators. Too high or too low doses will produce adverse effects and are related to the vitamin A concentration in plasma, liver and kidneys.
    Vitamin A Propionate
  • HY-Y0123
    DL-Tyrosine
    		98.0%
    DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine).
    DL-Tyrosine
  • HY-N7992
    Myricetin-3-O-rutinoside
    Myricetin-3-O-rutinoside is a Myricetin (HY-15097) derivative that can be found in the needles of Picea abies (Norway spruce). Myricetin-3-O-rutinoside exhibits certain anti-inflammatory activity.
    Myricetin-3-O-rutinoside
  • HY-W011927R
    4,4'-Sulfonyldiphenol (Standard)
    4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone) (Standard) is the analytical standard of 4,4'-Sulfonyldiphenol (HY-W011927). This product is intended for research and analytical applications. 4,4'-Sulfonyldiphenol, a substitute for Bisphenol A (HY-18260), is widely used in industrial and consumer products. 4,4'-Sulfonyldiphenol is an estrogen receptor (ER) agonist and can competitively bind to thyroid hormone receptors (TR) with IC50 values for TRα and TRβ are 2650 μM and 2294 μM respectively, thereby affecting breast development and reducing the expression of androgen receptor (AR) in fetal testes. 4,4'-Sulfonyldiphenol promotes the progression of glioblastoma by upregulating the EZH2 mediated PI3K/AKT/mTOR pathway. Under chronic exposure, 4,4'-Sulfonyldiphenol can cause significant lipid deposition and dyslipidemia in the mouse liver by upregulating JunB and Atf3, and has a role in causing obesity at low doses. 4,4'-Sulfonyldiphenol induces intestinal inflammation by altering the intestinal microbiome. 4,4'-Sulfonyldiphenol accelerates the progression of atherosclerosis in zebrafish embryo larvae.
    4,4'-Sulfonyldiphenol (Standard)
  • HY-157739
    1,2-Dioleoyl-3-arachidoylglycerol
    		99.0%
    1,2-Dioleoyl-3-arachidoylglycerol (AOO) is a triacylglycerol that can be isolated from soybean oil.
    1,2-Dioleoyl-3-arachidoylglycerol
  • HY-B1022
    Dimesna
    		98.0%
    Dimesna (BNP-7787), the disulfide form of Mesna (HY-13679), is a platinum-related toxicity protective agent. Dimesna converts to Mesna, which in turn inactivates toxic platinum substances. Dimesna does not interfere with the antitumor activity of platinum compounds. Dimesna does not affect the antiproliferative effects of Cisplatin (HY-17394) or Carboplatin (HY-17393). Dimesna counteracts Cisplatin-induced nephrotoxicity. Dimesna exerts selective protective effects on the kidneys. Dimesna can be used in studies related to ovarian cancer and Cisplatin-induced nephrotoxicity.
    Dimesna
  • HY-N15663
    (-)-Epigallocatechin-3-O-(4-O-methyl)gallate
    		99.40%
    (-)-Epigallocatechin-3-O-(4-O-methyl)gallate is an orally active catechin derivative found in Taiwanese oolong tea. (-)-Epigallocatechin-3-O-(4-O-methyl)gallate can inhibit histamine release and exhibits anti-inflammation and anti-allergic effect. (-)-Epigallocatechin-3-O-(4-O-methyl)gallate can be used for the researches of immunology and inflammation, such as type I allergic.
    (-)-Epigallocatechin-3-O-(4-O-methyl)gallate
  • HY-165836
    Para-nitrophenyl oleate
    		99.81%
    Para-nitrophenyl oleate is an ester product.
    Para-nitrophenyl oleate
  • HY-W094214
    Monomethyl itaconate
    		99.45%
    Monomethyl itaconate (β-Methyl itaconate) is a monomethyl ester derivative of Itaconic acid (HY-Y0520). Monomethyl itaconate can copolymerize with PEGMA to form pH-sensitive hydrogels.
    Monomethyl itaconate
  • HY-W140465
    L-Homotyrosine
    L-Homotyrosine is a tyrosine derivative that can be used for solid-phase peptide synthesis.
    L-Homotyrosine
  • HY-N8558
    Senkyunolide N
    		99.16%
    Senkyunolide N, a phthalide, can be isolated from rhizome of Ligusticum Chuanxiong.
    Senkyunolide N
  • HY-W016704
    2,5-Dihydroxybenzoic acid sodium
    		99.58%
    2,5-Dihydroxybenzoic acid (sodium) (Gentisic acid (sodium)) is a phenolic compound. 2,5-Dihydroxybenzoic acid (sodium) restores mean arterial pressure and reduces blood lactate concentration in animal models of sepsis and septic shock. 2,5-Dihydroxybenzoic acid (sodium) can be used in the study of septic shock related diseases.
    2,5-Dihydroxybenzoic acid sodium
  • HY-156206
    C24 Dihydro ceramide (d18:0/24:0)
    		99.0%
    C24 Dihydro ceramide (d18:0/24:0) is an ester product.
    C24 Dihydro ceramide (d18:0/24:0)
  • HY-W282663
    Henicosan-11-ol
    		99.91%
    Henicosan-11-ol (11-Heneicosanol) is an ester product.
    Henicosan-11-ol