ABT-770
ABT-770 (compound 11) is a highly selective and orally active MMP inhibitor, demonstrating over 1000-fold selectivity for MMP-2 (IC50=4 nM) compared to MMP-1 (IC50=4600 nM). ABT-770 can be utilized in studies related to tumor growth, invasion, and metastasis.
For research use only. We do not sell to patients.
- CAS No.: 220614-50-6
- Formula: C22H22F3N3O6
- Molecular Weight:481.42
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
MMP-2 4 nM (IC50) |
MMP-1 4600 nM (IC50) |
Chemical Information
-
CAS No. 220614-50-6
-
Molecular Weight 481.42
-
Formula C22H22F3N3O6
-
SMILES
O=CN([C@@H](CN(C(NC1(C)C)=O)C1=O)COC2=CC=C(C3=CC=C(OC(F)(F)F)C=C3)C=C2)O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)