CM112
CM112 is a selective protein arginine methyltransferase 1 (PRMT1) degrader by tethering hydrophobic tag, adamantane, to MS023 with a 5-PEG linker. CM112 induces the degradation of PRMT1 in various solid cancer cell lines. CM112 can also target the nonenzymatic function of PRMT1 by downregulating the stability of the orphan receptor TR3. CM112 is promising for research of cancers.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C39H61N5O7
- Molecular Weight:711.93
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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PRMT1 |
Chemical Information
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Molecular Weight 711.93
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Formel C39H61N5O7
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SMILES
O=C(CCOCCOCCOCCOCCOCCNC(CC12C[C@@H](C[C@H]3C2)C[C@@H](C3)C1)=O)NC4=CC=C(C5=CNC=C5CN(CCN)C)C=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)