Lambertellin
Lambertellin is an effective antibiotic that can be used as a bactericide and as a fungicide. Lambertellin exerts its anti-inflammatory effect in LPS (HY-D1056)-stimulated RAW 264.7 macrophage cells by modulating the activation of the MAPK and NF-κB signaling pathways.
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- CAS. Nr.: 28980-51-0
- Formel: C14H8O5
- Molecular Weight:256.21
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
In Vitro
In lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells, Lambertellin exhibits promising inhibitory activity against nitric oxide (NO) production with an IC50 value of 3.19 µM, and it significantly inhibits the expression of inducible NO synthase (iNOS) and cyclooxygenase 2 (COX-2). Lambertellin also decreases the expression of pro-inflammatory cytokines IL-6 and IL-1β[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 28980-51-0
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Molecular Weight 256.21
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Formel C14H8O5
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SMILES
O=C1OC(C(C2=C3C=CC=C2O)=O)=C(C=C1C)C3=O
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Structure Classification
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Initial Source
Lambertella sp.
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Lambertellin Related Classifications
HY-124508 Related Classifications
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