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Art. -Nr.: HY-N1305

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Sideritoflavone

(Synonyms: Sideritiflavone)

Sideritoflavone is a flavonoid. Sideritoflavone can be isolated from Baccharis densiflora. Sideritoflavone is toxic to JIMT-1 breast cancer cells.

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CAS. Nr.: 70360-12-2
Formel: C₁₈H₁₆O₈
Molecular Weight:360.31

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Sideritoflavone Chemical Structure

CAS. Nr.: 70360-12-2

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Bioz

Biologische Aktivität

Beschreibung

Sideritoflavone is a flavonoid. Sideritoflavone can be isolated from Baccharis densiflora. Sideritoflavone is toxic to JIMT-1 breast cancer cells^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
B16-F10	IC₅₀	5.6 μM Compound: 10	Anti-inflammatory activity in LPS-stimulated mouse B16-F10 cells assessed as reduction in TNFalpha production measured for 12 hrs by ELISA method Anti-inflammatory activity in LPS-stimulated mouse B16-F10 cells assessed as reduction in TNFalpha production measured for 12 hrs by ELISA method	[PMID: 37683361]
RBL-2H3	IC₅₀	>500 μM Compound: 9	Antihistaminic activity in rat RBL2H3 cells assessed as inhibition of DNP-BSA-induced beta-hexosaminidase release preincubated for 10 mins before DNP-BSA challenge Antihistaminic activity in rat RBL2H3 cells assessed as inhibition of DNP-BSA-induced beta-hexosaminidase release preincubated for 10 mins before DNP-BSA challenge	[PMID: 14510616]
THP-1	IC₅₀	12.4 μM Compound: 10	Anti-inflammatory activity in LPS-stimulated human THP-1 cells assessed as reduction of TNFalpha measured for 12 hrs by ELISA method Anti-inflammatory activity in LPS-stimulated human THP-1 cells assessed as reduction of TNFalpha measured for 12 hrs by ELISA method	[PMID: 37683361]

Chemical Information

CAS. Nr. 70360-12-2
Molecular Weight 360.31
Formel C₁₈H₁₆O₈
SMILES

O=C1C=C(C2=CC=C(O)C(O)=C2)OC3=C(OC)C(OC)=C(OC)C(O)=C13
Synonyms

Sideritiflavone
Structure Classification
- Flavonoids
- Flavones
Initial Source
- Plants
- Compositae
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Wendy Soria Sotillo, et al. Breast cancer cell line toxicity of a flavonoid isolated from Baccharis densiflora. BMC Complement Med Ther. 2021, 21, 2. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass

Konzentration

Volumen

Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biologische Aktivität
- Beschreibung
Chemical Information
Reinheit & Dokumentation
Verweise

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