Cat. No.: HY-L007

Immunology/Inflammation Compound Library

89 Cited Publications

Customer Review

Based on 89 publication(s) in Google Scholar

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. Inflammation is also the body's attempt at self-protection to remove harmful stimuli and begin the healing process. It’s part of the body's immune response. The immune system recognizes damaged cells, irritants, and pathogens, and inflammation begins the healing process. Inflammatory abnormalities are a large group of disorders that underlie a vast variety of human diseases. The immune system is often involved with inflammatory disorders, demonstrated in both allergic reactions and some myopathies, with many immune system disorders resulting in abnormal inflammation.

MCE designs a unique collection of 8,477 compounds that are useful tool for Immunology/Inflammation research or autoimmune inflammatory diseases drug discovery.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

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Description & Advantages
Product Details
- Formulation
- Layout
- Container
- Storage
- Shipping
Publications (89)
Documentation
Composition

Description & Advantages

• A unique collection of 8,477 small molecules with biological activity used for Immunology/Inflammation research.

• The library contains compounds targeting Immunology/Inflammation-related enzyme such as CCR, COX, Interleukin Related, IRAK, MyD88, PDE, PD-1/PD-L1, TLR, and more.

• A useful tool for researching the mechanism behind Immunology/Inflammation, drug screening and other pharmaceutical and biological applications.

• Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

• Structurally diverse, medicinally active, and cell permeable.

• Rich documentation with structure, IC₅₀, and brief introduction.

• NMR and HPLC validated to ensure high purity and quality.

• All compounds are in stock and continuously updated.

Product Details

Formulation

A collection of 8,477 Immunology/Inflammation related compounds supplied as pre-dissolved Solutions or Solid

Solution: 8,217 compounds supplied in 10 mM solution, 223 compounds supplied in 2 mM solution, 37 compounds supplied in 3 mg/mL solution.

Layout

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates.
This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage

-80°C

Shipping

Blue ice or dry ice