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Cat. No.: HY-N20718

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Agastinol

Agastinol is a naturally sourced caspase-3 inhibitor. Agastinol inhibits the expression of caspase-3 and apoptosis induced by Etoposide (HY-13629) in human leukemia U937 cells. Agastinol can be used in leukemia-related research.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 413615-33-5
Formule: C₂₇H₂₈O₈
Masse moléculaire:480.51

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Agastinol Chemical Structure

CAS No.: 413615-33-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
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Classifications
Bioz

Activité biologique

Description

IC₅₀ & Target^[1]

Caspase 3

15.2 μg/mL (IC₅₀)

Voir tous les produits spécifiques à Isoform Caspase :

In Vitro

Agastinol (compound 1) inhibits the expression of caspase-3 in human leukemia U937 cells induced by Etoposide (HY-13629), with an IC₅₀ of 15.2 μg/mL^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 413615-33-5
Masse moléculaire 480.51
Formule C₂₇H₂₈O₈
SMILES

C(OC(=O)C1=CC=C(O)C=C1)[C@H]2[C@@H](OC[C@H]2CC3=CC(OC)=C(O)C=C3)C4=CC(OC)=C(O)C=C4
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
- Plants
- Labiatae
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Zielińska S, et al. Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae). Phytochemistry Reviews, 2014, 13: 391-416.

[2]. Lee C, et al. Agastinol and agastenol, novel lignans from Agastache rugosa and their evaluation in an apoptosis inhibition assay. Journal of natural products. 2002 Mar;65(3):414-6. [Content Brief]

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Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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Agastinol

Voir tous les produits spécifiques à Isoform Caspase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Agastinol Related Classifications

HY-N20718 Related Classifications