CEP-8983
CEP-8983 is a PARP-1 and PARP-2 inhibitor (IC50: 20 and 6 nM). CEP-8983 is an effective chemosensitizing agent, and can sensitize chemotherapy-resistant cell lines and subcutaneous xenografts to Temozolomide (HY-17364) and Camptothecin (HY-16560).
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- CAS No.: 374071-46-2
- Formule: C18H14N2O3
- Masse moléculaire:306.32
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
20 and 6 nM (PARP-1/2)[1].
Chemical Information
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CAS No. 374071-46-2
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Masse moléculaire 306.32
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Formule C18H14N2O3
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SMILES
COC1=CC=CC2=C1C3=C(C(NC4=O)=O)C4=C(CCC5)C5=C3N2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CEP-8983 Related Classifications
HY-14688 Related Classifications
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