STAT1 - signal transducer and activator of transcription 1 Gene

Also Known as CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 6772

About STAT1

Cytogenetic location: 2q32.2 Genomic coordinates (GRCh38): 2:190,969,149-191,014,171 (from NCBI)

This gene has 41 transcripts (splice variants), 328 orthologues, 6 paralogues and is associated with 6 phenotypes. Ubiquitous expression in lymph node (RPKM 79.1), appendix (RPKM 72.6) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the STAT protein family. In response to Cytokines and Growth Factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. The protein plays an important role in immune responses to viral, Fungal and mycobacterial pathogens. Mutations in this gene are associated with Immunodeficiency 31B, 31A, and 31C. [provided by RefSeq, Jun 2020]

STAT1 Products (14)

mRNA	Protein	Name
NM_001384880.1	NP_001371809.1	signal transducer and activator of transcription 1-alpha/beta isoform 1
NM_001384881.1	NP_001371810.1	signal transducer and activator of transcription 1-alpha/beta isoform 2
NM_001384882.1	NP_001371811.1	signal transducer and activator of transcription 1-alpha/beta isoform 3
NM_001384883.1	NP_001371812.1	signal transducer and activator of transcription 1-alpha/beta isoform 4
NM_001384884.1	NP_001371813.1	signal transducer and activator of transcription 1-alpha/beta isoform 5
NM_001384885.1	NP_001371814.1	signal transducer and activator of transcription 1-alpha/beta isoform 6
NM_001384886.1	NP_001371815.1	signal transducer and activator of transcription 1-alpha/beta isoform 7
NM_001384887.1	NP_001371816.1	signal transducer and activator of transcription 1-alpha/beta isoform 8
NM_001384888.1	NP_001371817.1	signal transducer and activator of transcription 1-alpha/beta isoform 9
NM_001384889.1	NP_001371818.1	signal transducer and activator of transcription 1-alpha/beta isoform 10
NM_001384890.1	NP_001371819.1	signal transducer and activator of transcription 1-alpha/beta isoform 11
NM_001384891.1	NP_001371820.1	signal transducer and activator of transcription 1-alpha/beta isoform 12
NM_007315.4	NP_009330.1	signal transducer and activator of transcription 1-alpha/beta isoform alpha
NM_139266.3	NP_644671.1	signal transducer and activator of transcription 1-alpha/beta isoform beta

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Références	Source
NOT enables DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	10820245	GOA
enables DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	9535918	GOA
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	11972023	GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	18035482	GOA
enables RNA polymerase II core promoter sequence-specific DNA binding	IDA IDA: Inferred from direct assay	23386060	GOA
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	22002246	GOA
enables double-stranded DNA binding	IDA IDA: Inferred from direct assay	9630226	GOA
enables enzyme binding	IPI IPI: Inferred from physical interaction	26479788	GOA
enables histone acetyltransferase binding	IPI IPI: Inferred from physical interaction	26479788	GOA
enables histone binding	IPI IPI: Inferred from physical interaction	26479788	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	8605877	GOA
enables promoter-specific chromatin binding	IDA IDA: Inferred from direct assay	26479788	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	8156998	GOA
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	9630226	GOA
enables transcription coactivator binding	IPI IPI: Inferred from physical interaction	22002246	GOA
enables transcription corepressor binding	IPI IPI: Inferred from physical interaction	23386060	GOA
enables tumor necrosis factor receptor binding	IPI IPI: Inferred from physical interaction	10848577	GOA
enables ubiquitin-like protein ligase binding	IPI IPI: Inferred from physical interaction	26479788	GOA

Biological Process GO Annotation	Evidence	Références	Source
involved in cell surface receptor signaling pathway via JAK-STAT	IDA IDA: Inferred from direct assay	11972023	GOA
involved in cellular response to interferon-beta	IDA IDA: Inferred from direct assay	28753426	GOA
involved in cellular response to interferon-beta	IMP IMP: Inferred from mutant phenotype	18035482	GOA
involved in cellular response to type II interferon	IDA IDA: Inferred from direct assay	11972023	GOA
involved in defense response to virus	IDA IDA: Inferred from direct assay	28753426	GOA
NOT involved in endothelial cell migration	IMP IMP: Inferred from mutant phenotype	16585190	GOA
involved in interleukin-27-mediated signaling pathway	IDA IDA: Inferred from direct assay	32270034	GOA
involved in interleukin-7-mediated signaling pathway	IDA IDA: Inferred from direct assay	29202461	GOA
involved in interleukin-9-mediated signaling pathway	IDA IDA: Inferred from direct assay	9535918	GOA
involved in negative regulation by virus of viral protein levels in host cell	IMP IMP: Inferred from mutant phenotype	15825084	GOA
involved in negative regulation of angiogenesis	IMP IMP: Inferred from mutant phenotype	16585190	GOA
involved in negative regulation of canonical NF-kappaB signal transduction	IMP IMP: Inferred from mutant phenotype	10848577	GOA
involved in negative regulation of endothelial cell proliferation	IMP IMP: Inferred from mutant phenotype	16585190	GOA
involved in positive regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	10973496	GOA
involved in positive regulation of DNA-templated transcription	IGI IGI: Inferred from genetic interaction	26479788	GOA
involved in positive regulation of DNA-templated transcription	IMP IMP: Inferred from mutant phenotype	26479788	GOA
involved in positive regulation of defense response to virus by host	IGI IGI: Inferred from genetic interaction	26479788	GOA
involved in positive regulation of defense response to virus by host	IMP IMP: Inferred from mutant phenotype	26479788	GOA
involved in positive regulation of erythrocyte differentiation	IMP IMP: Inferred from mutant phenotype	28283061	GOA
involved in positive regulation of interferon-alpha production	IDA IDA: Inferred from direct assay	28753426	GOA
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	10820245	GOA
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	18035482	GOA
NOT involved in regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	10820245	GOA
involved in regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	28753426	GOA
involved in renal tubule development	IMP IMP: Inferred from mutant phenotype	20861313	GOA
involved in response to interferon-beta	IMP IMP: Inferred from mutant phenotype	24882218	GOA
involved in response to type II interferon	IDA IDA: Inferred from direct assay	11972023	GOA
involved in tumor necrosis factor-mediated signaling pathway	IDA IDA: Inferred from direct assay	10848577	GOA
involved in type I interferon-mediated signaling pathway	IDA IDA: Inferred from direct assay	23386060	GOA
involved in type II interferon-mediated signaling pathway	IDA IDA: Inferred from direct assay	21268089	GOA
involved in type II interferon-mediated signaling pathway	IMP IMP: Inferred from mutant phenotype	26479788	GOA

Cellular Component GO Annotation	Evidence	Références	Source
part of ISGF3 complex	IPI IPI: Inferred from physical interaction	24065129	GOA
part of RNA polymerase II transcription regulator complex	IPI IPI: Inferred from physical interaction	8662591	GOA
located in chromatin	IDA IDA: Inferred from direct assay	18035482	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	10692450	GOA
colocalizes with nucleus	IDA IDA: Inferred from direct assay	26479788	GOA
is active in nucleus	IDA IDA: Inferred from direct assay	15322115	GOA
located in nucleus	IDA IDA: Inferred from direct assay	10692450	GOA
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	17275127	GOA
part of protein-containing complex	IDA IDA: Inferred from direct assay	26479788	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

STAT1 Protein Structure

STAT_int

STAT_alpha

STAT_bind

SH2

STAT1_TAZ2bind

0
200
400
600
750 a.a.

Protein Preferred Names	Protein Names
signal transducer and activator of transcription 1-alpha/beta	signal transducer and activator of transcription 1, 91kD

STAT1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Références
Intra	STAT1	P42224	IFNGR1	Homo sapiens	P15260	Competition Binding	8662591
Intra	STAT1	P42224	IFNGR1	Homo sapiens	P15260	Competition Binding	8156998
Intra	STAT1	P42224	IFNGR1	Homo sapiens	P15260	X-Ray Diffraction	15780933
Intra	STAT1	P42224	OTUD4	Homo sapiens	Q01804	Y2H Prey Pooling	25416956
Intra	STAT1	P42224	OTUD4	Homo sapiens	Q01804	Y2H Array	25416956
Intra	STAT1	P42224	STAT2	Homo sapiens	P52630	Pull Down	8605877
Intra	STAT1	P42224	STAT2	Homo sapiens	P52630	Crosslink	24065129
Intra	STAT1	P42224	STAT3	Homo sapiens	P40763	Anti Tag CoIP	33961781
Intra	STAT1	P42224	STAT2	Homo sapiens	P52630	Pull Down	26966684
Intra	STAT1	P42224	STAT2	Homo sapiens	P52630	Anti Tag CoIP	33961781
Intra	STAT1	P42224	STAT2	Homo sapiens	P52630	Anti Bait CoIP	15825084
Intra	STAT1	P42224	STAT2	Homo sapiens	P52630	BioID	35140242
Intra	STAT1	P42224	STAT3	Homo sapiens	P40763	Pull Down	26966684
Intra	STAT1	P42224	STAT3	Homo sapiens	P40763	BioID	35140242
Intra	STAT1	P42224	STAT3	Homo sapiens	P40763	Anti Tag CoIP	31462771
Intra	STAT1	P42224	STAT2	Homo sapiens	P52630	Anti Bait CoIP	17923090
Intra	STAT1	P42224	STAT3	Homo sapiens	P40763	Affinity Chrom	35140242
Intra	STAT1	P42224	JAK1	Homo sapiens	P23458	Anti Tag CoIP	32953130
Intra	STAT1	P42224	JAK1	Homo sapiens	P23458	Anti Tag CoIP	34950606
Intra	STAT1	P42224	JAK1	Homo sapiens	P23458	Anti Tag CoIP	34521819
Cross	STAT1	P42224	S	SARS-CoV-2	P0DTC2	Anti Tag CoIP	34950606
Cross	STAT1	P42224	N	SARS-CoV-2	P0DTC9	Anti Tag CoIP	34521819
Cross	STAT1	P42224	N	SARS-CoV-2	P0DTC9	Anti Tag CoIP	32953130
Intra	STAT1	P42224	EGFR	Homo sapiens	P00533	Anti Tag CoIP	24658140
Intra	STAT1	P42224	EGFR	Homo sapiens	P00533	Competition Binding	12070153
Intra	STAT1	P42224	DDB1	Homo sapiens	Q16531	Y2H	21988832
Intra	STAT1	P42224	DDB1	Homo sapiens	Q16531	Pull Down	21988832
Intra	STAT1	P42224	KPNA1	Homo sapiens	P52294	Anti Tag CoIP	17596301
Intra	STAT1	P42224	KPNA1	Homo sapiens	P52294	Pull Down	26966684
Intra	STAT1	P42224	E2F1	Homo sapiens	Q01094	TAP	20195357
Intra	STAT1	P42224	ERBB2	Homo sapiens	P04626	PLA	25241761
Intra	STAT1	P42224	ERBB2	Homo sapiens	P04626	Protein Array	16273093
Intra	STAT1	P42224	PTK2	Homo sapiens	Q05397	PLA	25241761
Intra	STAT1	P42224	EIF1AD	Homo sapiens	Q8N9N8	Validated Y2H	25416956
Intra	STAT1	P42224	EIF1AD	Homo sapiens	Q8N9N8	Y2H Array	25416956
Intra	STAT1	P42224	EIF1AD	Homo sapiens	Q8N9N8	Y2H Pooling	16189514
Intra	STAT1	P42224	RXRA	Homo sapiens	P19793	Pull Down	21988832
Intra	STAT1	P42224	FOS	Homo sapiens	P01100	Anti Bait CoIP	12788789
Intra	STAT1	P42224	RIGI	Homo sapiens	O95786	Anti Bait CoIP	24360797
Cross	STAT1	P42224	P27958-PRO_0000037566	Hepatitis C virus	P27958-PRO_0000037566	Anti Bait CoIP	15825084
Cross	STAT1	P42224	p03255-1	Human adenovirus C	P03255-1	Y2H	9881977
Cross	STAT1	P42224	p03255-1	Human adenovirus C	P03255-1	Anti Bait CoIP	9881977
Cross	STAT1	P42224	p03255-2	Human adenovirus C	P03255-2	Anti Bait CoIP	9881977
Cross	STAT1	P42224	polg_hcv1	Hepatitis C virus	P26664	Anti Bait CoIP	16940534
Cross	STAT1	P42224	polg_hcv1	Hepatitis C virus	P26664	Anti Tag CoIP	16940534
Cross	STAT1	P42224	P27958-PRO_0000037576	Hepatitis C virus	P27958-PRO_0000037576	Anti Tag CoIP	17275127

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant STAT1 Proteins

Cat. No.	Nom du produit	Accession	Pureté
HY-P71335	STAT1 Protein, Human	P42224-2 (M1-V712)	≥ 85%, as determined by reducing SDS-PAGE.
HY-P73628	STAT1 Protein, Human (sf9, His-GST)	P42224-2 (M1-V712)	≥ 90%, as determined by reducing SDS-PAGE.

STAT1 Anticorps

Cat. No.	Nom du produit	Application	Reactivity
HY-P80340	STAT1 Antibody (YA059)	WB, IP, FC	Human, Mouse
HY-P80340A	STAT1 Antibody (YA059) (PBS only)	WB, IP, FC	Human, Mouse
HY-P80341	STAT1 Antibody (YA667)	WB, ICC/IF	Human, Mouse
HY-P80342	STAT1 alpha Antibody (YA058)	WB, ICC/IF, IHC-P, IP, FC	Human
HY-P80478	Phospho-STAT1 (Ser727) Antibody (YA148)	WB, IHC-P	Human, Mouse
HY-P80855	Phospho-STAT1 (Ser727) Antibody (YA149)	WB, IHC-P	Human, Mouse, Rat
HY-P80855A	Phospho-STAT1 (Ser727) Antibody (YA149)(PBS only)	WB, IHC-P	Human, Mouse, Rat
HY-P80856	Phospho-STAT1 (Tyr701) Antibody	ICC/IF, WB, IHC-F, IHC-P, IP, ELISA	Human, Mouse, Rat, Monkey
HY-P80856A	Phospho-STAT1 (Tyr701) Antibody（PBS only）	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat, Monkey
HY-P85755	STAT1 Antibody (YA5447)	IHC-P, ICC/IF	Human, Rat, Mouse
HY-P85794	STAT1 Antibody (YA5486)	WB, ICC/IF, ELISA	Human, Dog,

Related Diseases

Diseases	Alias
Immunodeficiency 31b	IMD31B Immunodeficiency 31b, Mycobacterial And Viral Infections, Autosomal Recessive Autosomal Recessive Stat1 Deficiency Predisposition To Severe Viral Infection Due To Stat1 Deficiency Susceptibility To Viral And Mycobacterial Infections Due To Stat1 Deficiency Stat1 Deficiency, Autosomal Recessive Autosomal Recessive Immunodeficiency 31b, Mycobacterial And Viral Infections Stat1 Deficiency Autosomal Recessive Susceptibility To Mycobacterial And Viral Infections Mycobacterial And Viral Infections Due To Complete Stat1 Deficiency Immunodeficiency, Type 31b, Mycobacterial And Viral Infections, Autosomal Recessive
Immunodeficiency 31c	IMD31C Candidiasis, Familial, 7 Candf7 Candidiasis, Familial Chronic Mucocutaneous, Autosomal Dominant Autoimmune Enteropathy And Endocrinopathy-Susceptibility To Chronic Infections Syndrome Autoimmune Enteropathy And Endocrinopathy - Susceptibility To Chronic Infections Syndrome Immunodeficiency 31c, Chronic Mucocutaneous Candidiasis, Autosomal Dominant Autosomal Dominant Chronic Mucocutaneous Familial Candidiasis Autosomal Dominant Immunodeficiency 31c Familial Candidiasis 7 Chronic Mucocutaneous Candidiasis 7 Immunodeficiency 31c, Autosomal Dominant Immunodeficiency, Type 31c, Autosomal Dominant
Immunodeficiency 31a	Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Stat1 Deficiency IMD31A Immunodeficiency 31a, Mycobacteriosis, Autosomal Dominant Stat1 Deficiency, Autosomal Dominant Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Signal Transducer And Activator Of Transcription 1 Deficiency Msmd Due To Partial Signal Transducer And Activator Of Transcription 1 Deficiency Msmd Due To Partial Stat1 Deficiency Autosomal Dominant Immunodeficiency 31a, Mycobacteriosis Immunodeficiency, Type 31a, Mycobacteriosis, Autosomal Dominant
Chronic Mucocutaneous Candidiasis	Candidiasis, Chronic Mucocutaneous Cmc Candidiasis Chronic Mucocutaneous
Bronchiectasis	Polynesian Bronchiectasis Kartagener Syndrome Bronchiectasis Nos
Hypothyroidism	Thyroid Diseases Thyroid Disease Thyroid Deficiency Thyroid Insufficiency Dysfunction Thyroid Thyroid Dysfunction
Combined Immunodeficiency	Combined T Cell And B Cell Immunodeficiency Congenital Combined Immunodeficiency Syndrome With Combined Immunodeficiency Combined T And B Cell Immunodeficiency Combined Immunity Deficiency Combined Immunodeficiency Syndrome Combined T-Cell And B-Cell Immunodeficiency Lymphopenic Agammaglobulinaemia
Combined T And B Cell Immunodeficiency
Melanoma	Malignant Melanoma Cutaneous Melanoma Naevocarcinoma Malignant Melanomas
Mumps	Parotitis Due To Mumps Virus Mumps Nos Epidemic Parotitis Infectious Parotitis
Candidiasis	Systemic Candidiasis Invasive Candidiasis Disseminated Candidiasis Systemic Candida Infections Candidiasis, Invasive
Rabies	Lyssa Hydrophobia St Hubert Disease
Coccidioidomycosis	Valley Fever Primary Extrapulmonary Coccidioidomycosis Coccidioides Immitis Infection Coccidiosis Coccidioides Infection Coccidioidomycosis, Unspecified San Joaquin Fever California Disease Desert Fever Desert Rheumatism San Joaquin Valley Fever Enteric Coccidiosis Primary Pulmonary Coccidioidomycosis Acute Coccidioidomycosis Posadas Wernicke Disease
Histoplasmosis	Darling Disease Reticuloendotheliosis, X-Linked Infection By Histoplasma Capsulatum Histoplasma Infection Reticuloendothelial Cytomycosis Cytomycosis Darling Histoplasmosis African Histoplasmosis Histoplasmosis Duboisii
Thanatophoric Dysplasia, Type I	Thanatophoric Dysplasia Thanatophoric Dwarfism Thanatophoric Dysplasia Type 1 TD1 Td Thanatophoric Short Stature Thanatophoric Dwarfism Type 1 Thanatophoric Dysplasia Type I Platyspondylic Lethal Skeletal Dysplasia, San Diego Type Lethal Short-Limbed Platyspondylic Dwarfism, San Diego Type Skeletal Dysplasia, San Diego Type Plsd San Diego Type Thanatophoric Dwarfism 1 Dwarfism Thanatophoric Dwarf, Thanatophoric Thanatophoric Dysplasia 1 Lethal Short-Limbed Platyspondylic Dwarfism San Diego Type Platyspondylic Lethal Skeletal Dysplasia San Diego Type Thanatophoric Dwarf Thanatophoric Dwarfism Or Short Stature Thanatophoric Dwarfism Syndrome Td - [Thanatophoric Dwarfism]
Measles	Rubeola Morbilli Measles Nos Koplik Spots
Herpes Simplex	Herpes Simplex Infections Herpesvirus Hominis Disease Herpes Simplex Disease Herpesviral Infection Due To Herpes Simplex Infections Due To Simplex Virus Herpes Nos
Myocarditis	Myocardial Inflammation Inflammatory Cardiomyopathy
Fibrosarcoma	Neoplasms, Fibrous Tissue Fibrocytic Tumor Fibrosarcoma Of Soft Tissue Fibrous Tissue Neoplasm
Vaccinia
Fanconi Anemia, Complementation Group C	Fanconi Anemia Complementation Group C FANCC Facc Fac Fa3 Fanconi Pancytopenia Type 3 Fanconi Pancytopenia, Type 3 Faces Syndrome Facial Features , Anorexia, Cachexia, Eye And Skin Anomalies Friedman-Goodman Syndrome Abnormality Of The Face
Hepatitis B	Chronic Hepatitis B Hepatitis B Infection Serum Hepatitis HBV Hepatitis B Chronic Hbv, Susceptibility To Hepatitis B, Chronic Chronic Hepatitis B Without Delta Agent Chronic Hbv - [Hepatitis B Virus] Infection Hepatitis B Nos Chronic Type B Viral Hepatitis Hep B Nos
Inflammatory Bowel Disease	Inflammatory Bowel Diseases Bowel Disease, Inflammatory
Hepatitis	Chronic Hepatitis Chronic Persistent Hepatitis Acute Hepatitis Hepatitis, Chronic Acute And Subacute Liver Necrosis Acute/Subac. Necrosis Of Liver Animal Hepatitis Hepatitis Chronic Hepatitis A Hepatitis, Animal Hepatitis Due To Toxoplasmosis Hepatitis In Toxoplasmosis Toxoplasmal Hepatitis Chronic Hepatitis, Unspecified Chronic Active Hepatitis Nec Other Specified Chronic Hepatitis Chronic Persistent Hepatitis Nec Chronic Lobular Hepatitis Nec
Yellow Fever	Urban Yellow Fever Jungle Yellow Fever Sylvatic Yellow Fever Yf Yellow Fever, Sylvan Bronze John Yellow Jack Yf- [Yellow Fever] Febris Flava
Trypanosomiasis
Laron Syndrome	Growth Hormone Insensitivity Syndrome Growth Hormone Receptor Deficiency Laron Dwarfism Pituitary Dwarfism Ii Laron-Type Isolated Somatotropin Defect Primary Growth Hormone Resistance Laron-Type Dwarfism Laron Type Pituitary Dwarfism I Primary Growth Hormone Insensitivity Primary Gh Resistance Gh-R Deficiency Growth Hormone Receptor Defect Laron-Type Pituitary Dwarfism Laron-Type Short Stature Severe Gh Insensitivity Ghis Short Stature Due To A Defect In Growth Hormone Receptor Or Post-Receptor Pathway Complete Growth Hormone Insensitivity Gh Receptor Deficiency Primary Gh Insensitivity Short Stature Due To Growth Hormone Resistance LARS
Viral Infectious Disease	Viral Disease Arbovirus Infections Virus Infection Virus Diseases Viral Infection Viral Infections Virus Infections
Nail Disease	Nail Diseases Abnormality Of The Nail Nail Anomaly
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Rosacea	Erythematotelangiectatic Rosacea Papulopustular Rosacea Phymatous Rosacea Acne Roscea Acne, Erythematosa Granulomatous Rosacea Ocular Rosacea Acne Rosacea Hypertrophic Rosacea
Osteomyelitis
Cd40 Ligand Deficiency	X-Linked Hyper Igm Syndrome Hyperimmunoglobulin M Syndrome Higm1 Hyper-Igm Syndrome Type 1 X-Linked Hyper-Igm Syndrome Xhigm Higmx-1 X-Linked Hyper-Igm Immunodeficiency Hyper-Igm Syndrome 1 Immunodeficiency With Hyper-Igm, Type 1 Hyper-Igm Syndrome Due To Cd40 Ligand Deficiency Hyper-Igm Syndrome Due To Cd40l Deficiency Hyper-Igm Immunodeficiency Syndrome Hyper-Igm Immunodeficiency Syndrome, Type 1
Immunodeficiency 35	Tyrosine Kinase 2 Deficiency IMD35 Tyk2 Deficiency Autosomal Recessive Hyper-Ige Syndrome With Atypical Mycobacteriosis Susceptibility To Infection Due To Tyk2 Deficiency Hyper-Ige Syndrome With Atypical Mycobacteriosis, Autosomal Recessive Hies With Atypical Mycobacteriosis, Autosomal Recessive Autosomal Recessiv Hies With Atypical Mycobacteriosis Autosomal Recessive Hyper-Ige Syndrome Due To Tyk2 Deficiency Autosomal Recessive Hies With Atypical Mycobacteriosis
Bronchitis	Chronic Bronchitis Acute Bronchitis Bronchitis, Chronic Acute Bronchitis And Bronchiolitis Chest Cold Chest Infection Ci - Chest Infection Recurrent Wheezy Bronchitis Bronchitis Chronic Lower Respiratory Tract Infection Acute Lower Respiratory Tract Infection Chronic Bronchitis Nos Senile Bronchitis Bronchitis Nos In Those Under L5 Years Of Age Bronchitis Nos
Polycythemia Vera	PV Polycythemia Rubra Vera Prv Osler-Vaquez Disease Chronic Erythremia Polycythaemia Rubra Vera Primary Polycythemia Vaquez Disease Polycythemia Vera, Somatic Osler-Vaquez Syndrome Proliferative Polycythaemia Polycythemia Ruba Vera Acquired Primary Erythrocytosis Heilmeyer-Schoner Disease Vaquez Osler Disease Primary Polycythaemia
Stomatitis
Endometrial Cancer	Endometrial Carcinoma Endometrial Neoplasm Malignant Neoplasm Of Endometrium Endometrioid Carcinoma Endometrial Neoplasms Carcinoma, Endometrioid Endometrial Cancer, Familial Endometrial Carcinoma, Somatic Endometrial Cancer, Susceptibility To Endometrial Ca Malignant Endometrial Neoplasm Neoplasm Of Endometrium Primary Malignant Neoplasm Of Endometrium Tumor Of Endometrium Carcinoma Of The Endometrium Endometrioid Carcinoma Of Female Reproductive System ENDMC Carcinoma Endometrioid Endometrial Cancers Cancer, Endometrial Uterine Corpus Cancer
Immunodeficiency 28	IMD28 Ifngr2 Deficiency Immunodeficiency 28, Mycobacteriosis, Autosomal Recessive Immunodeficiency 28, Mycobacteriosis Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Ifngammar2 Deficiency Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Interferon Gamma Receptor 2 Deficiency Msmd Due To Complete Ifngammar2 Deficiency Msmd Due To Complete Interferon Gamma Receptor 2 Deficiency Autosomal Recessive Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Ifngammar2 Deficiency Autosomal Recessive Msmd Due To Partial Ifngammar2 Deficiency Autosomal Recessive Msmd Due To Partial Interferon Gamma Receptor 2 Deficiency Autosomal Recessive Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Interferon Gamma Receptor 2 Deficiency Immunodeficiency, Type 28, Mycobacteriosis
Immunodeficiency 27b	Autosomal Dominant Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Ifngammar1 Deficiency IMD27B Immunodeficiency 27b, Mycobacteriosis, Autosomal Dominant Ifngr1 Deficiency, Autosomal Dominant Autosomal Dominant Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Interferon Gamma Receptor 1 Deficiency Autosomal Dominant Msmd Due To Partial Ifngammar1 Deficiency Autosomal Dominant Msmd Due To Partial Interferon Gamma Receptor 1 Deficiency Immunodeficiency 27b, Mycobacteriosis, Ad Autosomal Dominant Ifngr1 Deficiency Autosomal Dominant Immunodeficiency 27b, Mycobacteriosis Immunodeficiency, Type 27b, Mycobacteriosis, Autosomal Dominant
Achondroplasia, Severe, With Developmental Delay And Acanthosis Nigricans	SADDAN Saddan Dysplasia Severe Achondroplasia With Developmental Delay And Acanthosis Nigricans Severe Achondroplasia-Developmental Delay-Acanthosis Nigricans Syndrome Ssb Syndrome Skeleton Skin Brain Syndrome Skeleton-Skin-Brain Syndrome Achondroplasia
Crimean-Congo Hemorrhagic Fever	Crimean Hemorrhagic Fever Cchf Congo Hemorrhagic Fever Hemorrhagic Fever, Crimean Chf Congo Virus Congo-Crimean Hemorrhagic Fever Congo Fever Hemorrhagic Fever Crimean-Congo Cchf - [Crimean-Congo Haemorrhagic Fever] Kara Mikh Typhoid Fever Xīnjiāng Haemorrhagic Fever
Monocytic Leukemia	Monocytic Leukaemia Schilling'S Leukaemia Schilling'S Leukemia M5b Acute Differentiated Monocytic Leukemia
Macs Syndrome	Macrocephaly, Alopecia, Cutis Laxa, And Scoliosis Mycobacterium Avium Complex Disease Rin2 Syndrome Mycobacterium Avium-Intracellulare Infection Tall Forehead, Sparse Hair, Skin Hyperextensibility, And Scoliosis Mycobacterium Avium Complex Mycobacterium Avium Infection Infection Due To Mycobacterium Intracellulare Mac Disease Macrocephaly-Alopecia-Cutis Laxa-Scoliosis Syndrome Rin2 Deficiency Tall Forehead-Sparse Hair-Skin Hyperextensibility-Scoliosis Syndrome MACS Macrocephaly Alopecia Cutis Laxa And Scoliosis Syndrome
Acute Promyelocytic Leukemia	Leukemia, Acute Promyelocytic Acute Myeloblastic Leukemia Type 3 Aml M3 APL Leukemia, Acute Promyelocytic, Somatic Aml With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Apml Acute Myeloblastic Leukemia 3 Acute Myeloid Leukemia With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Acute Myeloblastic Leukaemia Type 3 Acute Myeloid Leukaemia M3 Acute Myeloid Leukemia M3 Acute Promyelocytic Leukaemia M3 Anll Myeloid Leukemia, Acute, M3 Leukemia Promyelocytic Acute Leukemia, Promyelocytic, Acute Leukemia, Acute, Promyelocytic
Multiple Sclerosis	MS Multiple Sclerosis, Susceptibility To Disseminated Sclerosis Multiple Sclerosis, Disease Progression, Modifier Of Insular Sclerosis Multiple Sclerosis Modifier Of Disease Progression Multiple Sclerosis, Susceptibility To 1 Multiple Sclerosis, Susceptibility To, 1 Multiple Sclerosis 1 Generalized Multiple Sclerosis Multiple Sclerosis Variant Multiple Sclerosis Susceptibility To Cerebrospinal Sclerosis Generalised Multiple Sclerosis Ms - [Multiple Sclerosis] Disseminated Cerebrospinal Sclerosis Disseminated Multiple Sclerosis Disseminated Nervous System Myelosclerosis Multiple Cerebrospinal Sclerosis Multiple Combined Sclerosis Multiple Sclerosis Generalised Disseminated Brain Sclerosis Disseminated Spinal Sclerosis Insular Brain Sclerosis Miliary Brain Sclerosis Multiple Combined Sclerosis Of Spinal Cord Multiple Ascending Sclerosis Multiple Brain Sclerosis Multiple Sclerosis Of Brain Stem Multiple Sclerosis Of The Brain Stem Multiple Sclerosis Of Cord Sclérose En Plaques Plaque Sclerosis Multiple Sclerosis Of The Spinal Cord
Immunodeficiency 27a	IMD27A Autosomal Recessive Ifngr1 Deficiency Autosomal Recessive Immunodeficiency 27a, Mycobacteriosis Autosomal Recessive Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Ifngammar1 Deficiency Autosomal Recessive Mendelian Susceptibility To Mycobacterial Diseases Due To Partial Interferon Gamma Receptor 1 Deficiency Autosomal Recessive Msmd Due To Partial Ifngammar1 Deficiency Autosomal Recessive Msmd Due To Partial Interferon Gamma Receptor 1 Deficiency Immunodeficiency 27a, Mycobacteriosis, Autosomal Recessive Ifngr1 Deficiency, Autosomal Recessive Immunodeficiency 27a, Mycobacteriosis, Ar Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Ifngammar1 Deficiency Msmd Due To Complete Ifngammar1 Deficiency Msmd Due To Complete Interferon Gamma Receptor 1 Deficiency Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Interferon Gamma Receptor 1 Deficiency Familial Disseminated Atypical Mycobacterial Infection Interferon Gamma, Receptor 1, Deficiency Immunodeficiency, Type 27a, Mycobacteriosis, Ar Mycobacterial Disease, Mendelian Susceptibility To
Vascular Disease	Vascular Diseases Aneurysm Spinal Cord Ischemia Vascular Anomaly Spinal Cord Vascular Diseases Vascular Tissue Disease
Hyper Ige Recurrent Infection Syndrome 1	Job Syndrome Hyper-Ige Recurrent Infection Syndrome 1 Hyperimmunoglobulin E Syndrome Job'S Syndrome Recurring Cold Staphylococcal Abscesses Ige Syndromes Buckley Syndrome Hie - [Hyperimmunoglobulin E] Syndrome Job-Buckley Syndrome Quie-Hill Syndrome
Microphthalmia With Limb Anomalies	Waardenburg Anophthalmia Syndrome Ophthalmoacromelic Syndrome OAS MLA Anophthalmia-Syndactyly Anophthalmia-Syndactyly Syndrome Anophthalmos With Limb Anomalies Anophthalmia Waardenburg Syndrome Anophthalmos-Syndactyly Ophthalmo-Acromelic Syndrome Anophthalmia-Waardenburg Syndrome Anophthalmos-Limb Anomalies Syndrome Syndactyly-Anophthalmos Syndrome Microphthalmia, With Limb Anomalies
Proteasome-Associated Autoinflammatory Syndrome 1	Jmp Syndrome Nakajo-Nishimura Syndrome Nkjo Autoinflammation, Lipodystrophy, And Dermatosis Syndrome Proteasome-Associated Autoinflammatory Syndrome 1 And Digenic Forms Nakajo Syndrome PRAAS1 Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy And Elevated Temperature Syndrome Candle Joint Contractures, Muscular Atrophy, Microcytic Anemia, And Panniculitis-Induced Lipodystrophy Aldd Inflammation Joint Contractures - Muscle Atrophy - Microcytic Anemia - Panniculitis-Induced Lipodystrophy Nakajo Nishimura Syndrome Amyotrophy Fat Tissue Anomaly Japanese Autoinflammatory Syndrome With Lipodystrophy Jasl Joint Contractures Muscular Atrophy Microcytic Anemia And Panniculitis-Induced Lipodystrophy Nns Nodular Erythema With Digital Changes Secondary Hypertrophic Osteoperiostosis With Pernio
Opportunistic Mycosis	Opportunistic Mycoses Opportunistic Systemic Mycoses
Primary Cutaneous T-Cell Non-Hodgkin Lymphoma	Cutaneous T-Cell Lymphoma Cutaneous T Cell Lymphoma Lymphoma, T-Cell, Cutaneous Ctcl Lymphoma T-Cell Cutaneous
Osteochondrodysplasia	Skeletal Dysplasia Chondrodystrophy Congenital Anomaly Of Cartilage Osteochondrodysplasias Cartilage Development Disorder Osteochondrodysplasia Syndrome Dysplasia, Skeletal Mucopolysaccharidosis Iv
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]
Autoimmune Polyendocrine Syndrome	Autoimmune Polyendocrinopathy Autoimmune Polyglandular Failure Autoimmune Polyglandular Syndrome Polyendocrinopathies, Autoimmune Lloyd'S Syndrome Aps Polyendocrinopathies Autoimmune Polyendocrine Autoimmunity Syndrome Lloyd Syndrome Polyglandular Autoimmune Deficiency Progressive Pluriglandular Insufficiency Pluriglandular Autoimmune Atrophy Pluriglandular Autoimmune Syndrome Thyroid-Adrenocortical Insufficiency Syndrome
Immunodysregulation, Polyendocrinopathy, And Enteropathy, X-Linked	IPEX X-Linked Autoimmunity-Allergic Dysregulation Syndrome Xlaad Diarrhea, Polyendocrinopathy, Fatal Infection Syndrome, X-Linked Ipex Syndrome Insulin-Dependent Diabetes Mellitus Secretory Diarrhea Syndrome Iddm-Secretory Diarrhea Syndrome Dmsd Autoimmunity-Immunodeficiency Syndrome, X-Linked Enteropathy, Autoimmune, With Hemolytic Anemia And Polyendocrinopathy Xpid Diabetes Mellitus, Congenital Insulin-Dependent, With Fatal Secretory Diarrhea Immune Dysregulation-Polyendocrinopathy-Enteropathy-X-Linked Syndrome Polyendocrinopathy, Immune Dysfunction, And Diarrhea, X-Linked Autoimmune Enteropathy Type 1 Immunodeficiency, Polyendocrinopathy, And Enteropathy, X-Linked Immunodeficiency, Polyendocrinopathy, And Enteropathy, X-Linked, Formerly Immunodeficiency, Polyendocrinopathy, Enteropathy X-Linked Syndrome Immunodysregulation, Polyendocrinopathy And Enteropathy X-Linked Autoimmunity-Immunodeficiency Syndrome X-Linked Iddm Secretory Diarrhea Syndrome Polyendocrinopathy, Immune Dysfunction And Diarrhea X-Linked Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome Immunodeficiency Polyendocrinopathy, Enteropathy, X-Linked Syndrome X-Linked Autoimmunity-Immunodeficiency Syndrome Immunodeficiency, Polyendocrinopathy, And Enteropathy X-Linked Syndrome X-Linked Syndrome Of Polyendocrinopathy, Immune Dysfunction, And Diarrhea
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Fungal Infectious Disease	Mycoses Mycosis
Immunodeficiency 44	IMD44
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Susceptibility To Lung Cancer, Protection Against Adenocarcinoma Of Lung, Somatic Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Autoimmune Polyendocrine Syndrome Type 1	Whitaker Syndrome Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Autoimmune Polyglandular Syndrome I Polyglandular Type I Autoimmune Syndrome
Cervical Squamous Cell Carcinoma	Squamous Cell Carcinoma Of The Cervix Uteri Squamous Cell Carcinoma Of Cervix
Immunodeficiency 41 With Lymphoproliferation And Autoimmunity	Cd25 Deficiency Immunodeficiency Due To Cd25 Deficiency IMD41 Interleukin 2 Receptor, Alpha, Deficiency Of Il2ra Deficiency Immunodeficiency 41 Interleukin-2 Receptor Alpha Chain Deficiency Interleukin 2 Receptor Alpha Deficiency Interleukin-2 Receptor, Alpha Chain, Deficiency Of Immunodeficiency, Type 41 With Lymphoproliferation And Autoimmunity
Sting-Associated Vasculopathy With Onset In Infancy	Savi Sting-Associated Vasculopathy, Infantile Onset Sting-Associated Vasculopathy, Infantile-Onset
Leukemia, Chronic Myeloid	Chronic Myeloid Leukemia Chronic Myelogenous Leukemia CML Chronic Granulocytic Leukemia Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib Chronic Myeloid Leukaemia Chronic Granulocytic Leukaemia Chronic Myelogenous Leukaemia Myeloid Leukemia, Chronic Leukemia, Chronic Myelogenous Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic Cml - Chronic Myelogenous Leukemia Cgl Chronic Myelocytic Leukemia Leukemia, Chronic Myeloid, Atypical ACML Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative Myeloid Leukemia Chronic Leukemia, Myeloid, Chronic Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative Cml- [Chronic Myeloid Leukaemia] Cgl - [Chronic Granulocytic Leukaemia] Chronic Myelocytic Leukaemia
Immunodeficiency 21	Monocytopenia And Mycobacterial Infection Syndrome Monomac Gata2 Deficiency Monocytopenia With Susceptibility To Infections Dcml IMD21 Dendritic Cell, Monocyte, B Lymphocyte, And Natural Killer Lymphocyte Deficiency Monocytopenia With Susceptibility To Mycobacterial, Fungal, And Papillomavirus Infections And Myelodysplasia Combined Immunodeficiency With Susceptibility To Mycobacterial, Viral, And Fungal Infections Combined Immunodeficiency With Susceptibility To Mycobacterial, Viral And Fungal Infections Dendritic Cell, Monocyte, B And Nk Lymphoid Deficiency Monocyte-B-Natural Killer-Dendritic Cell Deficiency Syndrome Monocytopenia With Mycobacterial, Fungal, And Papillomavirus Infections And Myelodysplasia Combined Immunodeficiency With Mycobacterial, Viral, And Fungal Infections Monocyte - B - Natural Killer - Dendritic Cell Deficiency Combined Immunodeficiency With Susceptibility To Mycobacterial Viral And Fungal Infections Dendritic Cell Monocyte Lymphocyte B And Natural Killer Lymphocyte Deficiency Monocytopenia With Susceptibility To Mycobacterial Fungal And Papillomavirus Infections And Myelodysplasia
Hyper Ige Syndrome	Hyper-Ige Syndrome Hyper Immunoglobulin E Syndrome Hies Hyper-Ige Recurrent Infection Syndrome Hyperimmunoglobulin E Syndrome Hyper Ige Job Syndrome Hartnup Disease
Primary Systemic Mycosis
Asthma	Chronic Obstructive Asthma Asthma, Diminished Response To Antileukotriene Treatment In Bronchial Hyperreactivity Asthma, Susceptibility To Asthma, Bronchial Asthma, Protection Against Asthma, Nocturnal, Susceptibility To Nocturnal Asthma Asthma-Related Traits Asthma-Related Traits, Susceptibility To Asthma, Nocturnal Chronic Obstructive Asthma With Acute Exacerbation Chronic Obstructive Asthma With Status Asthmaticus Exercise Induced Asthma Exercise-Induced Asthma Bronchial Asthma Asthma, Exercise-Induced Idiosyncratic Asthma Unspecified Asthma With Acute Exacerbation Asthma, Unspecified, With Stated Status Asthmaticus Status Asthmaticus Nos Acute Severe Asthma Acute Severe Bronchial Asthma Status Asthma Status Post Asthmaticus
Mycobacterium Tuberculosis 1	Tuberculosis Tuberculoma Tuberculosis, Susceptibility To Mycobacterium Tuberculosis, Susceptibility To, 1 Mtbs1 TB
B Cell Deficiency	Immunoglobulin Heavy Chain Deficiency B Cell Deficiencies Immunoglobulin Heavy Chain Deletion Humoral Immune Defect
Fanconi Anemia, Complementation Group A	Fanconi Anemia Fanconi Pancytopenia Fanconi Anemia Complementation Group A FANCA Fa Fanconi Panmyelopathy Fanconi'S Anemia Fanconi Anaemia Fanconi'S Anaemia Fanconi Hypoplastic Anemia Estren-Dameshek Variant Of Fanconi Anemia Estren-Dameshek Variant Of Fanconi Pancytopenia Fanconi Anemia Estren-Dameshek Variant Fanconis Anemia
Sarcoidosis 1	Sarcoidosis Boeck Sarcoid Besnier-Boeck-Schaumann Disease SS1 Sarcoidosis, Susceptibility To, 1 Lymphogranulomatosis Hodgkin Disease Boeck'S Disease Boeck'S Sarcoid Schaumann'S Disease Or Syndrome Hutchinson-Boeck Disease Or Syndrome
Chickenpox	Varicella Varicella Nos
Human Immunodeficiency Virus Infectious Disease	Hiv Infections
Thrombocytopenia	Low Platelet Count Low Platelets Decreased Platelets Platelet Dysfunction Nos
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Herpangina	Vesicular Pharyngitis
Salmonellosis	Salmonella Infections Salmonella Infection
Coccidiosis	Intestinal Coccidiosis Enteric Coccidiosis
Maxillary Sinus Adenocarcinoma	Adenocarcinoma Of Maxillary Sinus Adenocarcinoma Of The Maxillary Sinus
Aicardi-Goutieres Syndrome	Aicardi Goutieres Syndrome Cree Encephalitis Aicardi-Goutières Syndrome Encephalopathy With Basal Ganglia Calcification Ags Encephalopathy With Intracranial Calcification And Chronic Lymphocytosis Of Cerebrospinal Fluid Pseudotoxoplasmosis Syndrome Encephalopathy, Familial Infantile, With Calcification Of Basal Ganglia And Chronic Cerebrospinal Fluid Lymphocytosis Familial Infantile Encephalopathy With Intracranial Calcification And Chronic Cerebrospinal Fluid Lymphocytosis Aicardi-Goutieres Syndrome 1
Pancreatic Cancer	Pancreatic Carcinoma Carcinoma Of Pancreas Familial Pancreatic Carcinoma Pancreatic Neoplasm Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Cancer Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Immune Deficiency Disease	Immunodeficiency Primary Immunodeficiency Primary Immunodeficiency Disease Immunologic Deficiency Syndromes Hypoimmunity Immune Deficiency Disorder Immunodeficiency Syndrome Immune Disorder Primary Immune Deficiency Disorder Immune System Diseases Human Immunodeficiency Virus Infection Hiv - [Human Immunodeficiency Virus Infection] Hiv Positive Nos Hiv Disease Acquired Immune Deficiency Syndrome-Related Complex Aids-Like Syndrome Aids-Related Complex Nos Arc - [Aids-Related Complex] Immunodeficiency Due To Human Immunodeficiency Virus Infection Unspecified Human Immunodeficiency Virus Disease Hiv Disease Nos Human Immunodeficiency Virus Positive Nos Hiv Nos Deficiency Of Complement Initial Pathway Deficiency Of Complement Terminal Pathway Cfdd - [Complement Factor D Deficiency] Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency Nonfamilial Hypogammaglobulinaemia Common Variable Immune Deficiency Nonfamilial Agammaglobulinaemia Common Variable Agammaglobulinaemia Agammaglobulinaemia Nos Agammaglobulinaemia Antibody Deficiency Syndrome Hypogammaglobulinaemia Antibody Deficiency Syndrome Acquired Agammaglobulinaemia Nos Hypogammaglobulinaemia Nos Hyper Igm
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Crisponi/Cold-Induced Sweating Syndrome 2	Cold-Induced Sweating Syndrome 2 CISS2 Sweating Syndrome, Cold-Induced, Type 2
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Medulloblastoma	MDB Cpnet Localized Primitive Neuroectodermal Tumor Classic Medulloblastoma Medulloblastoma Predisposition Syndrome Medulloblastoma, Somatic Brain Medulloblastoma Cns Pnet Infratentorial Primitive Neuroectodermal Tumor Neuroectodermal Tumors, Primitive Medulloblastomas Desmoplastic Medulloblastoma Medulloblastoma, With Extensive Nodularity Medulloblastoma Of Unspecified Site Medullomyoblastoma Of Unspecified Site
Osteoporosis	Postmenopausal Osteoporosis Osteoporosis, Postmenopausal Bone Mineral Density Quantitative Trait Locus Bmnd Osteoporosis, Involutional Osteoporosis, Susceptibility To Osteoporosis, Postmenopausal, Susceptibility Bone Mineral Density Variation Qtl, Osteoporosis OSTEOP Involutional Osteoporosis Senile Osteoporosis Osteoporosis Postmenopausal Bone Mineral Density, Quantitative Trait Locus Osteoporosis, Senile Idiopathic Osteoporosis Bone Rarefaction Nos Type 1 Osteoporosis
T-Cell Acute Lymphoblastic Leukemia	T-Cell Leukemia Acute T Cell Leukemia Precursor T Lymphoblastic Leukemia Precursor T-Lymphoblastic Lymphoma/Leukemia T Acute Lymphoblastic Leukemia T-Cell Acute Lymphocytic Leukaemia T-Cell Lymphoblastic Leukemia/Lymphoma Leukemia T-Cell Leukemia, T-Cell Leukemia, Acute, Lymphoblastic, T-Cell Leukemia, T-Cell Acute Lymphoblastic Leukemia, Acute T-Cell Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Precursor T-Cell Lymphoblastic Lymphoma Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Cystic Fibrosis	Mucoviscidosis CF Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis Cystic Fibrosis Lung Disease, Modifier Of Cystic Fibrosis Of Pancreas Fibrocystic Disease Of Pancreas Cf - [Cystic Fibrosis] Cystic Fibrosis Nos Fibrocystic Disease Fibrocystic Disease Of The Pancreas Mucoviscidosis Of Pancreas Nonproliferative Fibrocystic Disease Pancreatic Cystic Fibrosis
Potocki-Shaffer Syndrome	Proximal 11p Deletion Syndrome Chromosome 11p11.2 Deletion Syndrome Pss 11p11.2 Deletion P11pds Defect11 Syndrome Deletion Of Chromosome 11p11.2 POSHS
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Omenn Syndrome	Histiocytic Medullary Reticulosis Severe Combined Immunodeficiency With Hypereosinophilia Combined Immunodeficiency With Hypereosinophilia Reticuloendotheliosis, Familial, With Eosinophilia Reticuloendotheliosis Familial With Eosinophilia Familial Reticuloendotheliosis Omenn'S Syndrome OS Malignant Histiocytosis
Essential Thrombocythemia	Essential Thrombocytosis Familial Thrombocytosis Hemorrhagic Thrombocythemia Hereditary Thrombocythemia Primary Thrombocytosis Idiopathic Thrombocythemia Primary Thrombocythemia Thrombocythemia, Essential Essential Thrombocythaemia Et Familial Thrombocythemia Thrombocythemia Essential
Myeloma, Multiple	Multiple Myeloma Plasma Cell Myeloma Kahler Disease Myelomatosis Medullary Plasmacytoma Multiple Myeloma, Resistance To Myeloma Plasma Cell Dyscrasia Kahler'S Disease Multiple Myeloma, Susceptibility To Myeloma - Multiple Kahler-Bozzolo Disease Plasma Cell Myelomas MM Plasma Cell Neoplasm Primary Systemic Amyloidosis Primary Amyloidosis Immunoglobulin Deposition Disease Plasmacytic Myeloma Multiple Myelomata Multiple Myeloma Nos Multiple Myeloma Without Mention Of Remission Monostotic Plasma Cell Myeloma Mm - [Multiple Myeloma]
Autoimmune Lymphoproliferative Syndrome	ALPS Canale-Smith Syndrome Autoimmune Lymphoproliferative Syndrome, Type Ia Autoimmune Lymphoproliferative Syndrome, Type Ib Autoimmune Lymphoproliferative Syndrome Type 1, Autosomal Dominant Css Autoimmune Lymphoproliferative Syndrome, Type 1b Autoimmune Lymphoproliferative Syndrome, Type 1a Autoimmune Lymphoproliferative Syndrome, Type I, Autosomal Dominant Fas Deficiency Autoimmune Lymphoproliferative Syndrome 1a ALPS1A Autoimmune Lymphoproliferative Syndrome Type Ia Autoimmune Lymphoproliferative Syndrome 1b ALPS1B Autoimmune Lymphoproliferative Syndrome Type Ib
Severe Combined Immunodeficiency	Scid Severe Combined Immunodeficiency Disease Combined T And B Cell Inborn Immunodeficiency Immunodeficiency, Severe Combined Scid - [Severe Combined Immunodeficiencies]
Body Mass Index Quantitative Trait Locus 11	OBESITY Obesity, Susceptibility To Leanness, Inherited Obesity, Susceptibility To, Bmiq11 Obesity, Mild, Early-Onset Obesity, Association With Obesity, Early-Onset, Susceptibility To Obesity, Severe Obesity, Severe, And Type Ii Diabetes Obesity, Late-Onset Obesity , Susceptibility To BMIQ11 Obesity Bmiq11 Obesity, Early-Onset Simple Obesity Nos Excess Fat Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified Adiposis
Skin Disease	Skin Diseases Genodermatosis Abnormality Of The Skin Skin Diseases, Genetic Skin And Subcutaneous Tissue Disease Dermatologic Disorders
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers
Behcet Syndrome	Behcet Disease Behcet'S Syndrome Behcet'S Disease Behçet Disease Bd Adamantiades-Behcet Disease Triple Symptom Complex Behçet'S Disease Behet'S Syndrome Bd Syndrome Behçet Syndrome Behçet'S Syndrome Behcet Triple Symptom Complex Malignant Aphthosis Old Silk Route Disease Adamantiades-Behçet Disease
Type 2 Diabetes Mellitus	Insulin Resistance NIDDM Type 2 Diabetes Diabetes Mellitus, Non-Insulin-Dependent T2D Noninsulin-Dependent Diabetes Mellitus Diabetes Mellitus, Type Ii Maturity-Onset Diabetes Insulin Resistance, Severe, Digenic Diabetes Mellitus, Type 2 Diabetes Mellitus, Noninsulin-Dependent Diabetes Mellitus, Noninsulin-Dependent, Association With Diabetes Mellitus, Noninsulin-Dependent, Late Onset Hypertension, Insulin Resistance-Related, Susceptibility To Insulin Resistance, Susceptibility To Non-Insulin-Dependent Diabetes Mellitus Type Ii Diabetes Mellitus Adult-Onset Diabetes Mellitus Maturity-Onset Diabetes Mellitus Diabetes Mellitus Type 2 Type Ii Diabetes Type 2 Diabetes Mellitus, Susceptibility To Diabetes, Type 2 Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 2, Susceptibility To Diabetes Mellitus, Noninsulin-Dependent, 2 Diabetes Mellitus, Type Ii, Susceptibility To Hypertension, Insulin Resistance-Related Adult-Onset Diabetes Aodm Diabetes Mellitus, Adult-Onset Diabetes Mellitus Type Ii Diabetes Mellitus Type 2, Susceptibility To Diabetes, Type Ii, Susceptibility To Diabetes Type 2 Diabetes Mellitus Adult Onset Diabetes Maturity Onset Diabetes Nonketotic Diabetes Non-Insulin Dependent Diabetes Mellitus T2dm - [Type 2 Diabetes Mellitus] Niddm - [Non Insulin Dependent Diabetes Mellitus] Dm2 Dm Type Ii Diabetic Type 2 Insulin Requiring Type 2 Diabetes Noninsulin Dependent Diabetes Non-Insulin-Dependent Diabetes Mellitus Without Complications Diabetes Due To Insulin Secretory Defect Diabetes Mellitus Due To Insulin Secretory Defect Non-Insulin-Dependent Diabetes Of The Young Senile Diabetes Nonketotic Hyperglycaemia Stable Diabetes
Celiac Disease 1	Celiac Disease Coeliac Disease Celiac Sprue Celiac Disease, Susceptibility To Gluten-Sensitive Enteropathy Nontropical Sprue Sprue CELIAC1 Celiac Disease, Susceptibility To, 1 Celiac Sprue 1 Celiac Sprue, Susceptibility To, 1 Gluten-Sensitive Enteropathy 1 Gluten-Sensitive Enteropathy, Susceptibility To, 1 Idiopathic Steatorrhea Cœliac Disease Gluten Intolerance Gluten-Induced Enteropathy Gluten Enteropathy Celiac Disease, Susceptibility To, Type 1 Childhood Celiac Disease Coeliac Rickets Gee Disease Gee-Herter Disease Heubner-Herter Disease Idiopathic Steatorrhoea Thaysen'S Disease Herter Gee Syndrome
Connective Tissue Disease	Connective Tissue Diseases Connective Tissue Disorder Abnormality Of Connective Tissue Disorder Of Connective Tissue Connective Tissue Disorders
Leukemia, Acute Myeloid	Acute Myeloid Leukemia Leukemia, Acute Myelogenous Acute Myelogenous Leukemia AML Leukemia, Acute Myeloid, Susceptibility To Acute Myeloblastic Leukemia Leukemia, Acute Myeloid, Reduced Survival In, Somatic Acute Myeloid Leukaemia Leukemia, Myelocytic, Acute Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome Secondary Aml Acute Myelocytic Leukemia Acute Myeloid Leukemia, Somatic Leukemia, Acute Myeloid, Somatic Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic Acute Myeloblastic Leukaemia Acute Myelogenous Leukaemia Aml - Acute Myeloid Leukemia Acute Myeloid Leukemia With Cebpa Somatic Mutations Aml With Cebpa Somatic Mutations Inherited Acute Myeloid Leukemia Familial Aml Inherited Aml Pure Familial Aml Pure Familial Acute Myeloid Leukemia Secondary Acute Myeloid Leukemia Therapy-Related Aml And Myelodysplastic Syndrome Acute Myeloid Leukemia, Secondary Acute Non-Lymphoblastic Leukemia Acute Non-Lymphocytic Leukemia Acute Biphenotypic Leukemia Acute Undifferentiated Leukemia Acute Myeloblastic Leukaemia With Multilineage Dysplasia Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Eye Disease	Eye Diseases Abnormality Of The Eye Toxoplasma Oculopathy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (1)

Cat. No.	Nom du produit	Effect	Pureté	Rare Diseases
HY-117287	Deucravacitinib	Inhibitor	99.93%	Unkown

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Nom du produit	Effect	Pureté	Phase
HY-112288	C188-9	Inhibitor	99.84%	Phase 2
HY-106981	Orazipone	Inhibitor	/	Phase 1

Pre-clinical Phase

Bioactive Molecules (38)

Cat. No.	Nom du produit	Effect	Pureté	Rare Diseases
HY-16997	Itacitinib	Inhibitor	99.97%	Yes
HY-W008510	2-Chloro-5-(trifluoromethyl)pyrimidine	Inducer	99.96%	Unkown
HY-115594	Erasin	Inhibitor	96.02%	Unkown
HY-173236	STAT4-IN-1	Inhibitor	99.17%	Unkown
HY-119024	BCI-137	Activator	99.84%	Unkown
HY-170621	STAT1/3-IN-1	Inhibitor	99.23%	Unkown
HY-116940	Sm4	Inhibitor	99.01%	Unkown
HY-122891	SB02024	Activator	99.70%	Unkown
HY-W031757	Anthraquinone-2-carboxylic acid	Inhibitor	98.0%	Unkown
HY-149209	LL-K8-22	Inhibitor	99.06%	Unkown
HY-169360	SD-436	Degrader	98.27%	Unkown
HY-158142	PROTAC TYK2 degrader-1	Inhibitor	99.55%	Unkown
HY-N12586	Pheophytin a	Inhibitor	80.0%	Unkown
HY-17663	KMR-206	Activator	98.86%	Unkown
HY-156466	QL-1200186	Inhibitor	99.95%	Unkown
HY-111493	LRRK2 inhibitor 1	Inhibitor	99.80%	Unkown
HY-161060	Zharp1-211	Inhibitor	99.15%	Unkown
HY-181792	ZDZ-553	Inhibitor	99.91%	Unkown
HY-173679	RBN012811	Activator	98.79%	Unkown
HY-181653	PROTAC SKP2 Degrader-1	Modulator	99.91%	Unkown
HY-16997A	Itacitinib adipate	Inhibitor	99.18%	Yes
HY-P1758A	IFN-α Receptor Recognition Peptide 1 acetate	Inhibitor	99.29%	Unkown
HY-P1758	IFN-α Receptor Recognition Peptide 1	Inhibitor	/	Unkown
HY-119956	Biflorin	Inhibitor	99.54%	Unkown
HY-114178	CDK8-IN-2	Inhibitor	/	Unkown
HY-178915	ITA-5	Inhibitor	/	Unkown
HY-183537	KSI-028	Inhibitor	/	Unkown
HY-184118	ADGRL1-IN-1	Activator	/	Unkown
HY-183554	Fa-Au	Activator	/	Unkown
HY-178916	ITA-9	Inhibitor	/	Unkown
HY-183937A	PD-305	Activator	/	Unkown
HY-184119	Pabgraminone C	Modulator	/	Unkown
HY-186227	ISS840	Inhibitor	/	Unkown
HY-183748	Polθ-IN-11	Activator	/	Unkown
HY-180226	Apoptosis inducer 55	Inhibitor	/	Unkown
HY-184592	JAK1-IN-21	Inhibitor	/	Unkown
HY-179288	TPST2-IN-1		/	Unkown
HY-178716	PTPN2/1-IN-4	Modulator	/	Unkown

Inhibitory Antibodies (2)

Cat. No.	Nom du produit	Effect	Pureté	Rare Diseases
HY-P99143	Anti-Mouse NK1.1 Antibody (PK136)	Inhibitor	98.57%	Unkown
HY-P992321	BAY-356	Activator	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	STAT1	VGNC	VGNC:56151
Rattus norvegicus	STAT1	RGD	RGD:3771
Macaca mulatta	STAT1	VGNC	VGNC:77904
Felis catus	STAT1	VGNC	VGNC:65759
Mus musculus	STAT1	MGD	MGI:103063
Others	STAT1	NCBI