NL-103
NL-103 is an inhibitor of histone deacetylases (HDACs) and Hedgehog, with the IC50 values of 21.3 nM, 57 nM, 74 nM, and 680 nM for HDAC1, HDAC2, HDAC3, and HDAC6, respectively. NL-103 can downregulate the expression of Gli2. NL-103 can be used in anti-cancer research.
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- CAS No.: 1788896-33-2
- Formule: C26H27Cl2N5O4
- Masse moléculaire:544.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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HDAC1 21.3 nM (IC50) |
HDAC2 57 nM (IC50) |
HDAC3 74 nM (IC50) |
HDAC6 680 nM (IC50) |
Chemical Information
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CAS No. 1788896-33-2
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Masse moléculaire 544.43
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Formule C26H27Cl2N5O4
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SMILES
O=C(C1=CN=C(NCCCCCCC(NO)=O)C=C1)NC2=CC=C(C(NC(C3=CC(Cl)=CC=C3)=O)=C2)Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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