Rodin-C
Rodin-C is a selective HDAC inhibitor with IC50s of 0.059, 0.18 and 5.39 μM for HDAC1, HDAC2 and HDAC11, respectively, over HDAC3-10. Rodin-C significantly inhibits the HDAC-CoREST complex with low hematological toxicity. Rodin-C can be used for neurologic disorders such as Alzheimer’s disease research.
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- CAS No.: 2065162-16-3
- Formule: C18H17FN6O
- Masse moléculaire:352.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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HDAC1 0.059 μM (IC50) |
HDAC2 0.18 μM (IC50) |
HDAC3 20.2 μM (IC50) |
HDAC4 >30 μM (IC50) |
HDAC5 >30 μM (IC50) |
HDAC6 >30 μM (IC50) |
HDAC7 >30 μM (IC50) |
HDAC8 >30 μM (IC50) |
HDAC9 >30 μM (IC50) |
HDAC10 >30 μM (IC50) |
HDAC11 5.39 μM (IC50) |
Chemical Information
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CAS No. 2065162-16-3
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Masse moléculaire 352.37
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Formule C18H17FN6O
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SMILES
O=C(N1CC2=NN(C)C=C2C1)NC3=NC(C4=CC=C(F)C=C4)=CC=C3N
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Rodin-C Related Classifications
HY-176868 Related Classifications
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