Thalidomide

26 Cited Publications
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Based on 26 publication(s) in Google Scholar

Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide can work as molecular glue to potentiate substrate.

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  • Pureté: 99.98%
  • CAS No.: 50-35-1
  • Formule: C13H10N2O4
  • Masse moléculaire:258.23
  • Stockage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 1 year , -20°C, 6 months
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