CEP-8983
CEP-8983 is a PARP-1 and PARP-2 inhibitor (IC50: 20 and 6 nM). CEP-8983 is an effective chemosensitizing agent, and can sensitize chemotherapy-resistant cell lines and subcutaneous xenografts to Temozolomide (HY-17364) and Camptothecin (HY-16560).
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- CAS. Nr.: 374071-46-2
- Formel: C18H14N2O3
- Molecular Weight:306.32
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
20 and 6 nM (PARP-1/2)[1].
Chemical Information
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CAS. Nr. 374071-46-2
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Molecular Weight 306.32
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Formel C18H14N2O3
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SMILES
COC1=CC=CC2=C1C3=C(C(NC4=O)=O)C4=C(CCC5)C5=C3N2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CEP-8983 Related Classifications
HY-14688 Related Classifications
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