Demethoxyfumitremorgin C
Demethoxyfumitremorgin C is a secondary metabolite of the marine fungus, Aspergillus fumigatus. Demethoxyfumitremorgin C induces prostate cancer cell apoptosis. Demethoxyfumitremorgin C activates caspase-3, -8, and -9, leading to PARP/ cleavage.
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- CAS. Nr.: 111768-16-2
- Formel: C21H23N3O2
- Molecular Weight:349.43
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| K562 | IC50 |
41 μM
Compound: 11
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Cytotoxicity against human K562 cells after 48 hrs by MTT assay
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
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[PMID: 19256529] |
Chemical Information
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CAS. Nr. 111768-16-2
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Molecular Weight 349.43
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Formel C21H23N3O2
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SMILES
C/C(C)=C\[C@@H]1N(C([C@@]2([H])N3CCC2)=O)[C@@](C3=O)([H])CC4=C1NC5=CC=CC=C45
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Demethoxyfumitremorgin C Related Classifications
HY-N7569 Related Classifications
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