FGA139
FGA139 is a cysteine proteases inhibitor with IC50 values of 4.98/3.14 μM for cathepsin B/L. FGA139 reduces LPS-induced NO production in RAW264.7 cells and tumor necrosis factor (TNFα) levels in microglia, and has anti-oxidative stress and anti-inflammatory activities. FGA139 promotes the secretion of neuroprotective metabolites purine and linoleic acid by LPS-stimulated microglia. FGA139 can be used in neuroinflammatory diseases research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C48H58BF2N7O5
- Molecular Weight:861.83
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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Molecular Weight 861.83
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Formel C48H58BF2N7O5
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SMILES
O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(/C=C/C(OCC)=O)=O)=O)[C@@H](N2N=NC(CCCCC3=C4[N+]([B-](F)(F)N5C3=C(C)C=C5C)=C(C)C=C4C)=C2)CC6=CC=CC=C6
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
FGA139 Related Classifications
HY-172977 Related Classifications
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