HDAC-IN-72
HDAC-IN-72 (compound 7j) is the most potent HDAC1 (IC50=0.65 μM), HDAC2 (IC50=0.78 μM), HDAC3 (IC50=1.70 μM) inhibitor and antiproliferative compound. HDAC-IN-72 can be used for breast cancer research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 763066-77-9
- Formel: C22H21N3O2
- Molecular Weight:359.42
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
|
HDAC1 0.65 μM (IC50) |
HDAC2 0.78 μM (IC50) |
HDAC3 1.70 μM (IC50) |
HDAC-IN-72 (0.1-50 μM, 48 h) shows good anti-proliferative activity against MCF-7 (IC50=0.83±1.41 μM) and T47D (IC50=1.4±1.85 μM) cell lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 763066-77-9
-
Molecular Weight 359.42
-
Formel C22H21N3O2
-
SMILES
O=C(NCC1=CC=C(C(NC2=CC=CC=C2N)=O)C=C1)C3=CC=C(C)C=C3
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)