TIQ-A
Based on 1 Customer Validation
TIQ-A is a potent TNKS (poly-ART, PARP) inhibitor, with an IC50 of 24 nM for TNKS2. TIQ-A is a potential anti-ischemic agent.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.85%
- CAS. Nr.: 420849-22-5
- Formel: C11H7NOS
- Molecular Weight:201.24
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Cell Cycle/DNA Damage Compound Library
HY-L004
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Epigenetics Compound Library
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Anti-Breast Cancer Compound Library
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Anti-Pancreatic Cancer Compound Library
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Heterocyclic Compound Library
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Highly Selective Inhibitors Library
HY-L158
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Anti-Ovarian Cancer Compound Library
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Multi-Target Compound Library
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
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High-Throughput Bioactive Compound Library
HY-L205
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MCE Kinase Hinge Binder Fragment Library
HY-L907
Biologische Aktivität
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TNKS2 24 nM (IC50) |
PARP2 210 nM (IC50) |
PARP15 230 nM (IC50) |
PARP10 >10 μM (IC50) |
PARP14 >10 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
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| HeLa | IC50 |
>100 μM
Compound: 1, TIQ-A
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Inhibition of tankyrase-1 function in human HeLa cells
Inhibition of tankyrase-1 function in human HeLa cells
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10.1039/C1MD00021G |
Chemical Information
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CAS. Nr. 420849-22-5
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Appearance Solid
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Molecular Weight 201.24
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Formel C11H7NOS
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Color Light green to green
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SMILES
O=C1NC2=C(C3=C1C=CC=C3)C=CS2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 125 mg/mL (621.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9692 mL | 24.8460 mL | 49.6919 mL | 124.2298 mL |
| 5 mM | 0.9938 mL | 4.9692 mL | 9.9384 mL | 24.8460 mL | |
| 10 mM | 0.4969 mL | 2.4846 mL | 4.9692 mL | 12.4230 mL | |
| 15 mM | 0.3313 mL | 1.6564 mL | 3.3128 mL | 8.2820 mL | |
| 20 mM | 0.2485 mL | 1.2423 mL | 2.4846 mL | 6.2115 mL | |
| 25 mM | 0.1988 mL | 0.9938 mL | 1.9877 mL | 4.9692 mL | |
| 30 mM | 0.1656 mL | 0.8282 mL | 1.6564 mL | 4.1410 mL | |
| 40 mM | 0.1242 mL | 0.6211 mL | 1.2423 mL | 3.1057 mL | |
| 50 mM | 0.0994 mL | 0.4969 mL | 0.9938 mL | 2.4846 mL | |
| 60 mM | 0.0828 mL | 0.4141 mL | 0.8282 mL | 2.0705 mL | |
| 80 mM | 0.0621 mL | 0.3106 mL | 0.6211 mL | 1.5529 mL | |
| 100 mM | 0.0497 mL | 0.2485 mL | 0.4969 mL | 1.2423 mL |
TIQ-A Related Classifications
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