Elaiomycin
Elaiomycin has activity against Gram-positive bacteria, some anaerobic bacteria, Eimeria tenella, E.acervulina.
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- CAS No.: 23315-05-1
- Formule: C13H26N2O3
- Masse moléculaire:258.36
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CWR22R | IC50 |
9.21 μM
Compound: 5
|
Cytotoxicity against human PRXF 22Rv1 cells by propidium iodide-based fluorescence assay
Cytotoxicity against human PRXF 22Rv1 cells by propidium iodide-based fluorescence assay
|
[PMID: 23013356] |
| HeLa | CC50 |
35.1 μg/mL
Compound: 5
|
Cytotoxicity against human HeLa cells
Cytotoxicity against human HeLa cells
|
[PMID: 23013356] |
| HT-29 | IC50 |
9.72 μM
Compound: 5
|
Cytotoxicity against human CXF HT29 cells by propidium iodide-based fluorescence assay
Cytotoxicity against human CXF HT29 cells by propidium iodide-based fluorescence assay
|
[PMID: 23013356] |
| HUVEC | GI50 |
30.4 μg/mL
Compound: 5
|
Antiproliferative activity against HUVEC
Antiproliferative activity against HUVEC
|
[PMID: 23013356] |
| K562 | GI50 |
>50 μg/mL
Compound: 5
|
Antiproliferative activity against human K562 cells
Antiproliferative activity against human K562 cells
|
[PMID: 23013356] |
Chemical Information
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CAS No. 23315-05-1
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Masse moléculaire 258.36
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Formule C13H26N2O3
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SMILES
CCCCCC/C=C\[N+]([O-])=N\[C@H]([C@@H](O)C)COC
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Structure Classification
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Initial Source
Streptomyces hepaticus.
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Anaerobic Bacterial Culture
Anaerobic bacterial culture detects viable bacteria that can grow under oxygen-depleted conditions; the readout is visible colony formation or broth turbidity after incubation in a chamber, jar, pouch, bag, or roll-tube system that maintains anaerobiosis. Oxygen control is central to the method because recovery depends on limiting oxygen exposure during collection, transport, inoculation, and incubation.
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)