MPT0G413
MPT0G413 (Compound 6) is a potent, selective, orally active and brain-penetrant HDAC6 inhibitor with an IC50 of 3.92 nM. MPT0G413 decreases not only the level of phosphorylation of tau proteins but also the aggregation of tau proteins. MPT0G413 can ameliorate the impaired learning and memory. MPT0G413 can be used for the research of neurological disease, such as Alzheimer's disease.
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- CAS No.: 2241643-23-0
- Formule: C24H20N2O4
- Masse moléculaire:400.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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HDAC6 3.92 nM (IC50) |
Chemical Information
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CAS No. 2241643-23-0
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Masse moléculaire 400.43
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Formule C24H20N2O4
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SMILES
O=C(NO)C1=CC=C(CN2C=CC3=C2C=CC(C(C4=CC=C(OC)C=C4)=O)=C3)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MPT0G413 Related Classifications
HY-141541 Related Classifications
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