Stigmalactam
Stigmalactam is an aristolactam-type alkaloid extracted from Orophea enterocarpa with anticancer effects. Stigmalactam induces apoptosis via the mitochondrial pathway, with the activation of caspase-3/9, and a decrease in mitochondrial membrane potential (MTP). Stigmalactam exhibits antioxidant activity by decreasing ROS production. Stigmalactam can be used for liver and breast cancer research.
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- CAS No.: 289499-72-5
- Formule: C18H15NO5
- Masse moléculaire:325.32
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Stigmalactam (24 h) dose-dependently inhibits HepG2, MDA-MB-231 and murine fibroblast NIH3T cells growth with IC50 values of 22.98, 33.23 and 24.44 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 289499-72-5
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Masse moléculaire 325.32
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Formule C18H15NO5
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SMILES
O=C1NC2=CC3=CC=C(C=C3C4=C2C1=C(OC)C(OC)=C4OC)O
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Structure Classification
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Stigmalactam Related Classifications
HY-N16535 Related Classifications
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