d-KLA Peptide-d30
d-KLA Peptide (D-(KLAKLAK)2)-d30 is the deuterium labeled d-KLA Peptide (HY-P10285). d-KLA Peptide, KLA peptide (HY-P5345) isomer, is a pro-apoptosis peptide. d-KLA Peptide can specifically target mitochondria and induce apoptosis by destroying the mitochondrial membrane. d-KLA Peptide increases caspase 3/7 activity, exerts proapoptotic activity and enhances antitumor efficacy in mouse melanoma models.
For research use only. We do not sell to patients.
- Formula: C72H108D30N20O15
- Molecular Weight:1554.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Caspase Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 286380-05-0
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Molecular Weight 1554.18
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Formula C72H108D30N20O15
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Synonyms
D-(KLAKLAK)2-d30
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Sequence
d-{Lys-{Leu-d10}-Ala-Lys-{Leu-d10}-Ala-Lys-Lys-{Leu-d10}-Ala-Lys-Leu-Ala-Lys}
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Sequence Shortening
d-{K-{Leu-d10}-AK-{Leu-d10}-AKK-{Leu-d10}-AKLAK}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)