CM112

CM112 is a selective protein arginine methyltransferase 1 (PRMT1) degrader by tethering hydrophobic tag, adamantane, to MS023 with a 5-PEG linker. CM112 induces the degradation of PRMT1 in various solid cancer cell lines. CM112 can also target the nonenzymatic function of PRMT1 by downregulating the stability of the orphan receptor TR3. CM112 is promising for research of cancers.

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  • Formel: C39H61N5O7
  • Molecular Weight:711.93
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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