IDE-IN-1
Based on 2 publication(s) in Google Scholar
IDE-IN-1 (compound 6bK) is an insulin-degrading enzyme (IDE) inhibitor with IC50 value of 50 nM. IDE-IN-1 can be used to study type 2 diabetes.
For research use only. We do not sell to patients.
- CAS No.: 1417537-93-9
- Formula: C41H55N7O7
- Molecular Weight:757.92
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) IDE-IN-1
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Biological Activity
Insulin-degrading Enzyme (IDE)
Chemical Information
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CAS No. 1417537-93-9
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Molecular Weight 757.92
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Formula C41H55N7O7
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SMILES
O=C(N[C@@H](C(NCCCC[C@H](NC(/C=C/C(N[C@H](C(N1)=O)CCCCN)=O)=O)C(N)=O)=O)CC2=CC=C(C=C2)C(C3=CC=CC=C3)=O)[C@@H]1CC4CCCCC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Mol Biomed
ML345 is a potent and selective NLRP3 inflammasome inhibitor with anti-inflammatory activity. [Abstract]2025 Nov 13;6(1):108. PMID: 41231359 -
Mol Med
Inhibition of insulin degrading enzyme suppresses osteoclast hyperactivity via enhancing Nrf2-dependent antioxidant response in glucocorticoid-induced osteonecrosis of the femoral head. [Abstract]2024 Jul 31;30(1):111. PMID: 39085816
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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