Copy Link Print Information

Linezolid

(Synonyms: PNU-100766)
54 Cited Publications
Revisión del cliente

Based on 54 publication(s) in Google Scholar

Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza: 99.94%
  • No. CAS: 165800-03-3
  • Fòrmula: C16H20FN3O4
  • Peso molecular:337.35
  • Almacenamiento:

    4°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • Linezolid Chemical Structure
    Linezolid Chemical Structure
  • Experimental Validation Results for Linezolid
  • Experimental Validation Results for Linezolid
  • Experimental Validation Results for Linezolid
  • Experimental Validation Results for Linezolid
  • Experimental Validation Results for Linezolid
No. CAS: 165800-03-3
Tamaño
Precio
Stock
Cantidad
Amount: USD 0.00
Please select quantity
or
or

* Seleccione Cantidad antes de agregar artículos.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Linezolid:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
  • Actividad biológica
  • Chemical Information
  • Solvente y solubilidad
  • Pureza y Documentación
  • Referencias
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Linezolid

More
Customer Validation & Images
Cell Proliferation/Viability AssayIn Vivo Efficacy StudyBio/Physico-chemical AssayWB
  • Cell Proliferation/Viability Assay
  • In Vivo Efficacy Study
  • Cell Proliferation/Viability Assay
  • Bio/Physico-chemical Assay
  • WB

Ver todos los productos específicos de isoformas Antibiotic

More
Keywords
100 mg

Obtener un presupuesto En stock

Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Inicie sesiòn
Registrar
Sign in to MedChemExpress
Registrar una cuenta nueva

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Linezolid Chemical Structure
    Linezolid Chemical Structure
    1/16
  • 1/16

    Linezolid purchased from MedChemExpress. Usage Cited in: Nat Microbiol. 2025 Nov;10(11):2875-2891. [Abstract]

    Customer Validation
     Dose-response curves for Linezolid (LZD: 0.0625-256 μg/mL) against M. abscessus ∆eis2 or M. abscessus Eis2 T258R strains complemented with pOLYG-aac(3)IV-eis2 overexpression or pOLYG-aac(3)IV control vector.

  • 1/16

    Linezolid purchased from MedChemExpress. Usage Cited in: Nat Microbiol. 2025 Nov;10(11):2875-2891. [Abstract]

    Customer Validation
     Efficacy of CLR, Linezolid (LZD: 100 mg/kg) and FF-NH2 versus saline vehicle in an acute mouse infection model. GM-CSF KO mice were infected with M. abscessus WT, treatment began on day 2 and continued for 9 days (CLR/LZD oral daily, FF-NH2 subcutaneous twice daily). Bacterial burden (colony forming units (c.f.u.)) was measured in lung, liver and spleen at day 12 post-infection.

  • 1/16

    Linezolid purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2023 Jul 1;242(Pt 1):124750. [Abstract]

    Customer Validation
     MH-S cells were pretreated with insulin, linezolid, or combination of insulin (50 nmol/L) and Linezolid (0.25 μg/ml) for 1 h, next these cells were treated with high glucose (30 mmol/L) and/or S. aureus 8325–4, high glucose and/or S. aureus DU1090 for 4 h, then the cell viability was tested by CCK8 kit;

  • 1/16

    Linezolid purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2023 Jul 1;242(Pt 1):124750. [Abstract]

    Customer Validation
     MH-S cells were pretreated with insulin, linezolid, or a combination of insulin (50 nmol/L) and linezolid (0.25 μg/ml) for 1 hour, and then treated with high glucose (30 mmol/L) and/or Staphylococcus aureus 8325-4, or high glucose and/or Staphylococcus aureus DU1090 for 4 hours. The glucose content in the MH-S cell culture medium was detected using a glucose content detection kit.

  • 1/16

    Linezolid purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2023 Jul 1;242(Pt 1):124750. [Abstract]

    Customer Validation
     MH-S cells were pretreated with insulin, linezolid and combination of insulin (50 nmol/L) and Linezolid (0.25 μg/ml) for 1 h, next these cells were treated with high glucose (30 mmol/L) and/or S. aureus 8325–4 (1 × 107 CFUs), high glucose and/or S. aureus DU1090 (1 × 107 CFUs) for 4 h. Then the expressions of TLR2, MAPKs (JNK, ERK, p38, p-JNK, p-ERK1/2, and p-p38), NLRP3 inflammasome proteins (NLRP3, ASC, Caspase-1, IL-1β, IL-18) and MIP-2 were detected by each pathway inhibitor treatment was used to further explore the upstream and downstream relationships among TLR2, MAPKs and NLRP3-related inflammatory pathways in MH-S cells.

  • Linezolid