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Referencia número: HY-N20718

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Agastinol

Agastinol is a naturally sourced caspase-3 inhibitor. Agastinol inhibits the expression of caspase-3 and apoptosis induced by Etoposide (HY-13629) in human leukemia U937 cells. Agastinol can be used in leukemia-related research.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 413615-33-5
Fòrmula: C₂₇H₂₈O₈
Peso molecular:480.51

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Agastinol Chemical Structure

No. CAS: 413615-33-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

IC₅₀ & Target^[1]

Caspase 3

15.2 μg/mL (IC₅₀)

Ver todos los productos específicos de isoformas Caspase :

In Vitro

Agastinol (compound 1) inhibits the expression of caspase-3 in human leukemia U937 cells induced by Etoposide (HY-13629), with an IC₅₀ of 15.2 μg/mL^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 413615-33-5
Peso molecular 480.51
Fòrmula C₂₇H₂₈O₈
SMILES

C(OC(=O)C1=CC=C(O)C=C1)[C@H]2[C@@H](OC[C@H]2CC3=CC(OC)=C(O)C=C3)C4=CC(OC)=C(O)C=C4
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
- Plants
- Labiatae
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Zielińska S, et al. Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae). Phytochemistry Reviews, 2014, 13: 391-416.

[2]. Lee C, et al. Agastinol and agastenol, novel lignans from Agastache rugosa and their evaluation in an apoptosis inhibition assay. Journal of natural products. 2002 Mar;65(3):414-6. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Agastinol

Ver todos los productos específicos de isoformas Caspase

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Agastinol Related Classifications

HY-N20718 Related Classifications