EVP-21
EVP-21 is a selective TRPML3 agonist with an EC50 of 4.3 μM for human TRPML3, and it is selective over TRPML1 and human TRPML2. EVP-21 elicits TRPML3 currents in late endosomes/lysosomes and early endosomes. EVP-21 can be used for research on TRPML3-related mechanisms such as emphysema, hearing loss, and yellow fever virus infection.
For research use only. We do not sell to patients.
- CAS No.: 2742654-01-7
- Formula: C16H19NO
- Molecular Weight:241.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
TRPML3 4.3 μM (EC50) |
Chemical Information
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CAS No. 2742654-01-7
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Molecular Weight 241.33
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Formula C16H19NO
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SMILES
CC1=C(C(C)=CC(C)=C1)C2=NOC3=C2CCCC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)