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LT-626

LT-626 is a potent PARP inhibitor with an IC50 of 1.60 nM. LT-626 inhibits cellular PAR synthesis with an EC50 of 17.9 nM and shows enhanced cytotoxicity in colorectal cancer cells harboring MRE11 mutations. LT-626 exhibits synergistic effects with Cisplatin (HY-17394), Oxaliplatin (HY-17371), and SN-38 (HY-13704) in colorectal cancer cells. LT-626 can be used for colorectal research.

For research use only. We do not sell to patients.

  • CAS No.: 1207456-03-8
  • Formula: C20H15F2N5O
  • Molecular Weight:379.37
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • LT-626 Chemical Structure
    LT-626 Chemical Structure
CAS No.: 1207456-03-8
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All PARP Isoforms

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  • LT-626 Chemical Structure
    LT-626 Chemical Structure
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  • LT-626