Leukotriene E4
Based on 1 publication(s) in Google Scholar
Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). Leukotriene E4 accumulates in both plasma and urine and urinary excretion of Leukotriene E4 is most often used as an indicator of asthma.
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- Pureza: 99.80%
- No. CAS: 75715-89-8
- Fòrmula: C23H37NO5S
- Peso molecular:439.61
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Almacenamiento:
Solution, -20°C, 2 years
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Actividad biológica
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Chemical Information
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Publications Citing Use of MedChemExpress (MCE) Leukotriene E4
MoreVer todos los productos específicos de isoformas Endogenous Metabolite
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Actividad biológica
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Human Endogenous Metabolite |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
9.83 μM
Compound: Leukotrien E4
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TP_TRANSPORTER: inhibition of E217betaG uptake (E217betaG: 0.055 uM) in membrane vesicles from Mrp2-expressing Sf9 cells
TP_TRANSPORTER: inhibition of E217betaG uptake (E217betaG: 0.055 uM) in membrane vesicles from Mrp2-expressing Sf9 cells
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[PMID: 11306690] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 75715-89-8
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Appearance Liquid
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Peso molecular 439.61
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Fòrmula C23H37NO5S
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Color Colorless to light yellow
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SMILES
CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SC[C@H](N)C(O)=O)[C@@H](O)CCCC(O)=O
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Synonyms
LTE4
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Solution, -20°C, 2 years
Publications (1)
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Journal Impact Factor
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Most Recent
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Nat Commun
2025 Dec 18;16(1):11205. PMID: 41413034
Pureza y Documentación
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Ficha de datos (238 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Leukotriene E4 Related Classifications
HY-113465 Related Classifications
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