Mazethramycin
Mazethramycin is an antitumor antibiotic that exerts its antitumor effect by interfering with cellular DNA replication and RNA synthesis. Mazethramycin can be used in cancer research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 68373-96-6
- Fòrmula: C17H19N3O4
- Peso molecular:329.35
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 68373-96-6
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Peso molecular 329.35
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Fòrmula C17H19N3O4
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SMILES
O=C(/C=C/C1=CN2C(C(NC3=C(C(C)=CC=C3C2=O)O)O)C1)NC
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Structure Classification
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Initial Source
Streptomyces thioluteus
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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PCNA Immunodetection Proliferation Assay
PCNA immunodetection measures proliferative activity by detecting proliferating cell nuclear antigen, a nuclear protein associated with DNA polymerase δ function and DNA replication. The assay readout is the proportion of PCNA-positive nuclei among total counted cells, but PCNA labeling is not identical to BrdU labeling because PCNA can mark late G1/early S-associated replication competence and may persist beyond active DNA synthesis depending on fixation and extraction conditions.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)