Mz325
Based on 1 Customer Validation
Mz325 is a dual inhibitor of HDAC and Sirt2, with the IC50 of 9.7 μM to Sirt2, that play an important role in pathogenesis of cancer and neurodegeneration.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.10%
- No. CAS: 3032670-12-2
- Fòrmula: C38H45N9O5S2
- Peso molecular:771.95
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
Descripciòn
Chemical Information
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No. CAS 3032670-12-2
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Appearance Solid
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Peso molecular 771.95
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Fòrmula C38H45N9O5S2
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Color White to off-white
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SMILES
O=C(NC1=NC=C(S1)CC2=CC=CC(OCC3=CN(N=N3)CCCCC(N(CC4=CC=C(C=C4)C(NO)=O)CCCC)=O)=C2)CSC5=NC(C)=CC(C)=N5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (129.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2954 mL | 6.4771 mL | 12.9542 mL | 32.3855 mL |
| 5 mM | 0.2591 mL | 1.2954 mL | 2.5908 mL | 6.4771 mL | |
| 10 mM | 0.1295 mL | 0.6477 mL | 1.2954 mL | 3.2386 mL | |
| 15 mM | 0.0864 mL | 0.4318 mL | 0.8636 mL | 2.1590 mL | |
| 20 mM | 0.0648 mL | 0.3239 mL | 0.6477 mL | 1.6193 mL | |
| 25 mM | 0.0518 mL | 0.2591 mL | 0.5182 mL | 1.2954 mL | |
| 30 mM | 0.0432 mL | 0.2159 mL | 0.4318 mL | 1.0795 mL | |
| 40 mM | 0.0324 mL | 0.1619 mL | 0.3239 mL | 0.8096 mL | |
| 50 mM | 0.0259 mL | 0.1295 mL | 0.2591 mL | 0.6477 mL | |
| 60 mM | 0.0216 mL | 0.1080 mL | 0.2159 mL | 0.5398 mL | |
| 80 mM | 0.0162 mL | 0.0810 mL | 0.1619 mL | 0.4048 mL | |
| 100 mM | 0.0130 mL | 0.0648 mL | 0.1295 mL | 0.3239 mL |