NL-103
NL-103 is an inhibitor of histone deacetylases (HDACs) and Hedgehog, with the IC50 values of 21.3 nM, 57 nM, 74 nM, and 680 nM for HDAC1, HDAC2, HDAC3, and HDAC6, respectively. NL-103 can downregulate the expression of Gli2. NL-103 can be used in anti-cancer research.
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- No. CAS: 1788896-33-2
- Fòrmula: C26H27Cl2N5O4
- Peso molecular:544.43
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
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HDAC1 21.3 nM (IC50) |
HDAC2 57 nM (IC50) |
HDAC3 74 nM (IC50) |
HDAC6 680 nM (IC50) |
Chemical Information
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No. CAS 1788896-33-2
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Peso molecular 544.43
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Fòrmula C26H27Cl2N5O4
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SMILES
O=C(C1=CN=C(NCCCCCCC(NO)=O)C=C1)NC2=CC=C(C(NC(C3=CC(Cl)=CC=C3)=O)=C2)Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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