2. Gene
  3. Faah - fatty acid amide hydrolase Gene

Faah - fatty acid amide hydrolase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 100911581 | Gene type: protein coding

About Faah

Primary_assembly 5: 129,479,824-129,498,677 reverse strand.mRatBN7.2:CM026978.1

This gene has 2 transcripts (splice variants), 131 orthologues, 1 paralogue and is associated with 6 phenotypes. Biased expression in Liver (RPKM 24.3), Brain (RPKM 57.9) and 6 other tissues.

Summary

Enables several functions, including acylglycerol Lipase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; and identical protein binding activity. Involved in fatty acid catabolic process; monoacylglycerol catabolic process; and positive regulation of vasoconstriction. Located in organelle membrane. Human ortholog(s) of this gene implicated in obesity and substance-related disorder. Orthologous to human FAAH (fatty acid amide hydrolase). [provided by Alliance of Genome Resources, Apr 2022]

Faah Products(1)

mRNA Protein Name
NM_001369126.1 NP_001356055.1 fatty-acid amide hydrolase 1

Faah Protein Structure

Amidase

Amidase: cl18951 (94 - 561)

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  • 579 a.a.
Protein Preferred Names Protein Names

fatty-acid amide hydrolase 1

anandamide amidase

anandamide amidohydrolase 1

fatty acid ester hydrolase

oleamide hydrolase 1

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0182 Carmofur Inhibitor 99.95% Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-14376 Redafamdastat Inhibitor 99.89% Phase 2
HY-19636 JNJ-42165279 Inhibitor 99.87% Phase 2
Pre-clinical Phase
Bioactive Molecules (61)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14595 Biochanin A Inhibitor 99.01% Unkown
HY-10864 URB-597 Inhibitor 98.96% Unkown
HY-119283 MAGL-IN-5 Inhibitor 99.73% Unkown
HY-15250 JZL195 Inhibitor 99.75% Unkown
HY-14380 PF-3845 Inhibitor 99.85% Unkown
HY-19740 BIA 10-2474 Inhibitor 99.39% Unkown
HY-N7062 JNJ-1661010 Inhibitor 99.77% Unkown
HY-10865 LY2183240 Inhibitor 98.01% Unkown
HY-79511 FAAH-IN-2 Inhibitor 98.17% Unkown
HY-116477 URB937 Inhibitor 99.85% Unkown
HY-136924 FP-Biotin 99.84% Unkown
HY-103337 N-Arachidonoylserotonin Inhibitor ≥98.0% Unkown
HY-125967 AM 374 Inhibitor ≥97.0% Unkown
HY-155773 VU534 Inhibitor 98.53% Unkown
HY-18544 AA38-3 Inhibitor 99.89% Unkown
HY-N2512 1-Monomyristin Inhibitor ≥98.0% Unkown
HY-123863 SSR411298 Inhibitor 99.75% Unkown
HY-18081 PF 750 Inhibitor 99.29% Unkown
HY-N2365 Macamide B Inhibitor 98.39% Unkown
HY-152254 CB2R/FAAH modulator-3 Inhibitor 99.71% Unkown
HY-103462 TC-F2 Inhibitor 99.75% Unkown
HY-127023 Eicosapentaenoyl serotonin Inhibitor ≥99.0% Unkown
HY-18080 SA 47 Inhibitor ≥99.0% Unkown
HY-N3033 N-​Benzyllinolenamide Inhibitor 99.70% Unkown
HY-10862 FAAH inhibitor 1 Inhibitor 98.91% Unkown
HY-103461 FAAH-IN-6 Inhibitor 99.70% Unkown
HY-111389 FAAH-IN-1 Inhibitor 99.93% Unkown
HY-10867 PF-622 Inhibitor / Unkown
HY-146342 FAAH/MAGL-IN-3 Inhibitor / Unkown
HY-148909 Isopropyl dodec-11-enylfluorophosphonate Inhibitor / Unkown
HY-157766 FAAH/TRPV1 blocker-1 Inhibitor / Unkown
HY-120961 Oleoyl ethyl amide Inhibitor / Unkown
HY-14595R Biochanin A (Standard) Inhibitor / Unkown
HY-116710 3-Decyl-5,5'-diphenyl-2-thioxo-4-imidazolidinone Inhibitor / Unkown
HY-B1227S1 Carprofen-13C,d3 / Unkown
HY-144738 Dual FAAH/sEH-IN-1 Inhibitor / Unkown
HY-149654 FAAH/cPLA2α-IN-1 Inhibitor / Unkown
HY-102054 Acetylhydrolase-IN-1 Inhibitor / Unkown
HY-118158 FAAH/MAGL-IN-4 Inhibitor 99.83% Unkown
HY-143263 FAAH/MAGL-IN-1 Inhibitor / Unkown
HY-103463 SA57 Inhibitor ≥99.0% Unkown
HY-B1227S Carprofen-d3 Inhibitor / Unkown
HY-143264 FAAH/MAGL-IN-2 Inhibitor / Unkown
HY-152253 CB2R/FAAH modulator-2 Inhibitor / Unkown
HY-151919 FAAH-IN-7 Inhibitor / Unkown
HY-N2428 N-(3-Methoxybenzyl)Palmitamide Inhibitor 99.96% Unkown
HY-146341 FAAH-IN-5 Inhibitor / Unkown
HY-152251 CB2R/FAAH modulator-1 Inhibitor / Unkown
HY-18013 JNJ-40355003 Inhibitor / Unkown
HY-139143 WWL154 Inhibitor / Unkown
HY-W728451 URB694 Inhibitor / Unkown
HY-121558 JP104 Inhibitor / Unkown
HY-147910 Carpro-AM1 Inhibitor / Unkown
HY-157132 FAAH-IN-8 Inhibitor / Unkown
HY-139384 FAAH inhibitor 2 Inhibitor / Unkown
HY-W751418 N-Nervonoyl taurine / Unkown
HY-77491 FAAH/MAGL-IN-5 Inhibitor 99.17% Unkown
HY-120650 CAY10435 Inhibitor / Unkown
HY-19636A JNJ-42165279 dihydrochloride Inhibitor / Unkown
HY-111199 JP83 Inhibitor / Unkown
HY-U00240 SA72 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Faah NCBI NCBI:2166