Tlr2 - toll-like receptor 2 Gene

Enables Lipopeptide binding activity. Involved in several processes, including neurogenesis; positive regulation of interleukin-10 production; and response to molecule of Bacterial origin. Located in cell body; cell projection; and cell surface. Used to study carotid stenosis; ileitis; keratitis; lung disease (multiple); and renal fibrosis. Biomarker of acute necrotizing pancreatitis; kidney failure; lung disease; pancreatitis; and perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dermatitis (multiple); gastrointestinal system Cancer (multiple); lung disease (multiple); and rhinitis (multiple). Orthologous to human TLR2 (toll like receptor 2). [provided by Alliance of Genome Resources, Apr 2022]