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Cat. No.: HY-157152

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HDAC-IN-65

HDAC-IN-65 ( compound 6) is a selective histone deacetylase (HDAC) inhibitor with IC₅₀ value of 2.5μM. HDAC-IN-65 is a prodrug with very good bioreductive properties.

For research use only. We do not sell to patients.

Formula: C₃₀H₃₀N₁₀O₅
Molecular Weight:610.62

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

HDAC-IN-65 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

HDAC-IN-65 ( compound 6) is a selective histone deacetylase (HDAC) inhibitor with IC₅₀ value of 2.5μM. HDAC-IN-65 is a prodrug with very good bioreductive properties^[1].

All HDAC Isoforms :

Chemical Information

Molecular Weight 610.62
Formula C₃₀H₃₀N₁₀O₅
SMILES

O=C(NC1=CC=CC=C1NC(C2=NC=C(N=C2)N3CCN(CC3)CC4=CNC5=C4C=CC=C5)=O)OCC6=CN=C(N6C)[N+]([O-])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mohamed Abdelsalam, et al. Design and synthesis of bioreductive prodrugs of class I histone deacetylase inhibitors and their biological evaluation in virally transfected acute myeloid leukemia cells. Arch Pharm (Weinheim). 2023. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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HDAC-IN-65

All HDAC Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

HDAC-IN-65 Related Classifications

HY-157152 Related Classifications

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