1. Cell Cycle/DNA Damage
    Epigenetics
    Autophagy
  2. HDAC
    Autophagy
  3. HDAC10-IN-1

HDAC10-IN-1 

Cat. No.: HY-144779
Handling Instructions

HDAC10-IN-1 (compound 13b) is a potent and highly selective HDAC10 inhibitor, with an IC50 of 58 nM. HDAC10-IN-1 modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells.

For research use only. We do not sell to patients.

HDAC10-IN-1 Chemical Structure

HDAC10-IN-1 Chemical Structure

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Description

HDAC10-IN-1 (compound 13b) is a potent and highly selective HDAC10 inhibitor, with an IC50 of 58 nM. HDAC10-IN-1 modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells[1].

IC50 & Target

HDAC10

58 ± 10 nM (IC50)

hHDAC8

920 ± 170 nM (IC50)

hHDAC6

2420 ± 530 nM (IC50)

Molecular Weight

313.39

Formula

C18H23N3O2

SMILES

CN1C=C(C2=C1C=CC=C2)CN3CCC(CC3)/C=C/C(NO)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
HDAC10-IN-1
Cat. No.:
HY-144779
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