HDAC10-IN-3
HDAC10-IN-3 (Compound 2a) is a potent HDAC10 inhibitor with an IC50s of 0.41, 37, 350 and 4500 nM against HDAC10, HDAC6, HDAC8 and HDAC1. HDAC10-IN-3 exhibits moderate cytotoxicity in KB and SK-OV-3 cells, but does not show significant cytotoxicity against most cancer cell lines. HDAC10-IN-3 can be used for the study of cancers.
For research use only. We do not sell to patients.
- Formula: C17H17N3O2
- Molecular Weight:295.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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hHDAC10 0.41 nM (IC50) |
hHDAC6 37 nM (IC50) |
hHDAC8 350 nM (IC50) |
hHDAC1 4500. nM (IC50) |
Chemical Information
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Molecular Weight 295.34
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Formula C17H17N3O2
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SMILES
O=C(NO)C1=CC=C(CNCC2=CNC3=C2C=CC=C3)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)