HDAC6-IN-48
HDAC6-IN-48 (compound 5i) is a potent and selective HDAC6 inhibitor with IC50 values of 5.16, 396.72, 638.08 nM for HDAC6, HDAC3, HDAC1, respectively. HDAC6-IN-48 induces apoptosis and cell cycle arrest at G0/G1 phase. HDAC6-IN-48 increases the protein expression of acetylated α-tubulin.
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- CAS. Nr.: 3052111-12-0
- Formel: C24H21N3O4
- Molecular Weight:415.44
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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HDAC6 5.16 nM (IC50) |
HDAC3 396.72 nM (IC50) |
HDAC1 638.08 nM (IC50) |
Chemical Information
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CAS. Nr. 3052111-12-0
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Molecular Weight 415.44
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Formel C24H21N3O4
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SMILES
COC1=CC=C(C=C1)C2=CC3=C(NC=C3CC(NC4=CC=C(C=C4)C(NO)=O)=O)C=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HDAC6-IN-48 Related Classifications
HY-163894 Related Classifications
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