HDAC6-IN-48
HDAC6-IN-48 (compound 5i) is a potent and selective HDAC6 inhibitor with IC50 values of 5.16, 396.72, 638.08 nM for HDAC6, HDAC3, HDAC1, respectively. HDAC6-IN-48 induces apoptosis and cell cycle arrest at G0/G1 phase. HDAC6-IN-48 increases the protein expression of acetylated α-tubulin.
For research use only. We do not sell to patients.
- CAS No.: 3052111-12-0
- Formula: C24H21N3O4
- Molecular Weight:415.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HDAC6 5.16 nM (IC50) |
HDAC3 396.72 nM (IC50) |
HDAC1 638.08 nM (IC50) |
Chemical Information
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CAS No. 3052111-12-0
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Molecular Weight 415.44
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Formula C24H21N3O4
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SMILES
COC1=CC=C(C=C1)C2=CC3=C(NC=C3CC(NC4=CC=C(C=C4)C(NO)=O)=O)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)