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Cat. No.: HY-184550

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HDAC6 ligand-9

HDAC6 ligand-9 (Compound 1a) is a ligands for target protein for PROTAC. HDAC6 ligand-9 can be used to synthesize PROTAC HDAC6 degrader-4 (HY-123971).

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CAS No.: 1206627-01-1
Formule: C₈H₁₇N₃O₃
Masse moléculaire:203.24

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

HDAC6 ligand-9 Chemical Structure

CAS No.: 1206627-01-1

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- In Vitro
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Description

HDAC6 ligand-9 (Compound 1a) is a ligands for target protein for PROTAC. HDAC6 ligand-9 can be used to synthesize PROTAC HDAC6 degrader-4 (HY-123971)^[1].

IC₅₀ & Target

^[1]

HDAC6

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In Vitro

Ligands of the target protein cause PROTAC to bind to the target protein, leading to its ubiquitination and subsequent degradation.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 1206627-01-1
Masse moléculaire 203.24
Formule C₈H₁₇N₃O₃
SMILES

O=C(NO)CCCCCCC(NN)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Yang K, et al.. Development of the first small molecule histone deacetylase 6 (HDAC6) degraders. Bioorganic & medicinal chemistry letters. 2018 Aug 01;28(14):2493-2497. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
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HDAC6 ligand-9

Voir tous les produits spécifiques à Isoform HDAC

Activité biologique

Description

IC50 & Target

In Vitro

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

HDAC6 ligand-9 Related Classifications

HY-184550 Related Classifications

Bioz

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