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Cat. No.: HY-184550

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HDAC6 ligand-9

HDAC6 ligand-9 (Compound 1a) is a ligands for target protein for PROTAC. HDAC6 ligand-9 can be used to synthesize PROTAC HDAC6 degrader-4 (HY-123971).

For research use only. We do not sell to patients.

CAS No.: 1206627-01-1
Formula: C₈H₁₇N₃O₃
Molecular Weight:203.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

HDAC6 ligand-9 Chemical Structure

CAS No.: 1206627-01-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

HDAC6 ligand-9 (Compound 1a) is a ligands for target protein for PROTAC. HDAC6 ligand-9 can be used to synthesize PROTAC HDAC6 degrader-4 (HY-123971)^[1].

IC₅₀ & Target^[1]

HDAC6

All HDAC Isoforms :

In Vitro

Ligands of the target protein cause PROTAC to bind to the target protein, leading to its ubiquitination and subsequent degradation.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1206627-01-1
Molecular Weight 203.24
Formula C₈H₁₇N₃O₃
SMILES

O=C(NO)CCCCCCC(NN)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yang K, et al.. Development of the first small molecule histone deacetylase 6 (HDAC6) degraders. Bioorganic & medicinal chemistry letters. 2018 Aug 01;28(14):2493-2497. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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HDAC6 ligand-9

All HDAC Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

HDAC6 ligand-9 Related Classifications

HY-184550 Related Classifications