1. Cell Cycle/DNA Damage Epigenetics
  2. HDAC
  3. HPB

HPB (HDAC6 inhibitor HPB) is a selective HDAC6 inhibitor with an IC50 of 31 nM. HPB exhibits >30-flod selectivity for HDAC6 over HDAC1.

For research use only. We do not sell to patients.

HPB Chemical Structure

HPB Chemical Structure

CAS No. : 1800066-24-3

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Based on 1 publication(s) in Google Scholar

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Description

HPB (HDAC6 inhibitor HPB) is a selective HDAC6 inhibitor with an IC50 of 31 nM. HPB exhibits >30-flod selectivity for HDAC6 over HDAC1[1].

IC50 & Target[1]

HDAC6

31 nM (IC50)

HDAC1

1130 nM (IC50)

Clinical Trial
Molecular Weight

328.36

Formula

C18H20N2O4

CAS No.
SMILES

O=C(N(CC1=CC=C(C(NO)=O)C=C1)CCO)CC2=CC=CC=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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HPB Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
HPB
Cat. No.:
HY-130493
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